Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)

This study aimed to study the inhibition activity of lactic acid bacteria probiotics deriving from Acehnese fermented Etawa goat’s milk (yogurt) against Streptococcus pyogenes bacterial infection in rats (Rattus norvegicus). Haematological analysis of the rats’ blood was performed on the following p...

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Main Authors: Novina Rahmawati, Maimun Syukri, Darmawi Darmawi, Indra Zachreini, Utari Zulfiani, Muhammad Yusuf, Rinaldi Idroes
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2022/2899462
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author Novina Rahmawati
Maimun Syukri
Darmawi Darmawi
Indra Zachreini
Utari Zulfiani
Muhammad Yusuf
Rinaldi Idroes
author_facet Novina Rahmawati
Maimun Syukri
Darmawi Darmawi
Indra Zachreini
Utari Zulfiani
Muhammad Yusuf
Rinaldi Idroes
author_sort Novina Rahmawati
collection DOAJ
description This study aimed to study the inhibition activity of lactic acid bacteria probiotics deriving from Acehnese fermented Etawa goat’s milk (yogurt) against Streptococcus pyogenes bacterial infection in rats (Rattus norvegicus). Haematological analysis of the rats’ blood was performed on the following parameters: platelets, leukocytes, lymphocytes, neutrophils, and monocytes, where the data were further processed using ANOVA and Duncan’s test with a confidence level of 95% (0.05). The results revealed that administering yogurt containing probiotics could reduce infections in the throats of rats caused by S. pyogenes. Based on the haematology examination, the probiotic yogurt could maintain the number of platelets, leukocytes, lymphocytes, neutrophils, and monocytes. Statistical significance was obtained when the infected rats were administered with a ±1.00 mL/day dose for seven days of treatment (p<0.05).
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institution Kabale University
issn 1537-744X
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-5252323f433b40fcbc16e5e5130c9a292025-02-03T01:20:08ZengWileyThe Scientific World Journal1537-744X2022-01-01202210.1155/2022/2899462Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)Novina Rahmawati0Maimun Syukri1Darmawi Darmawi2Indra Zachreini3Utari Zulfiani4Muhammad Yusuf5Rinaldi Idroes6Graduate School of Mathematics and Applied SciencesMedical FacultyFaculty of Veterinary MedicineMedical FacultyDepartment of ChemistryDepartment of ChemistryDepartment of ChemistryThis study aimed to study the inhibition activity of lactic acid bacteria probiotics deriving from Acehnese fermented Etawa goat’s milk (yogurt) against Streptococcus pyogenes bacterial infection in rats (Rattus norvegicus). Haematological analysis of the rats’ blood was performed on the following parameters: platelets, leukocytes, lymphocytes, neutrophils, and monocytes, where the data were further processed using ANOVA and Duncan’s test with a confidence level of 95% (0.05). The results revealed that administering yogurt containing probiotics could reduce infections in the throats of rats caused by S. pyogenes. Based on the haematology examination, the probiotic yogurt could maintain the number of platelets, leukocytes, lymphocytes, neutrophils, and monocytes. Statistical significance was obtained when the infected rats were administered with a ±1.00 mL/day dose for seven days of treatment (p<0.05).http://dx.doi.org/10.1155/2022/2899462
spellingShingle Novina Rahmawati
Maimun Syukri
Darmawi Darmawi
Indra Zachreini
Utari Zulfiani
Muhammad Yusuf
Rinaldi Idroes
Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)
The Scientific World Journal
title Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)
title_full Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)
title_fullStr Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)
title_full_unstemmed Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)
title_short Haematological Features of White Rats (Rattus norvegicus) Infected with S. pyogenes and Administered with Probiotics (Yogurt)
title_sort haematological features of white rats rattus norvegicus infected with s pyogenes and administered with probiotics yogurt
url http://dx.doi.org/10.1155/2022/2899462
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