Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project
Our study aimed to assess the prevalence of fall risk-increasing drugs (FRIDs) in a sample of community-residing older patients in Croatia and its association with negative health outcomes. An observational, cross-sectional study was conducted on older patients (65+) visiting community pharmacies in...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2024-12-01
|
| Series: | Acta Pharmaceutica |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acph-2024-0034 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832570354717949952 |
|---|---|
| author | Paar Elizabeta De Lai Eleonora Držaić Margita Kummer Ingrid Bužančić Iva Hadžiabdić Maja Ortner Brkic Jovana Fialová Daniela |
| author_facet | Paar Elizabeta De Lai Eleonora Držaić Margita Kummer Ingrid Bužančić Iva Hadžiabdić Maja Ortner Brkic Jovana Fialová Daniela |
| author_sort | Paar Elizabeta |
| collection | DOAJ |
| description | Our study aimed to assess the prevalence of fall risk-increasing drugs (FRIDs) in a sample of community-residing older patients in Croatia and its association with negative health outcomes. An observational, cross-sectional study was conducted on older patients (65+) visiting community pharmacies in three regionally different study sites in Croatia. Data were collected using a questionnaire developed for that purpose and included components of comprehensive geriatric assessment. Prevalence of FRIDs was identified using the “Screening Tool of Older Persons Prescriptions in older adults with high fall risk” (STOPPFall). In the sample of 407 participants (median age 73 (IQR 69–70) years; 63.9 % females), 79.1 % used at least one FRID. The most common drug classes were diuretics, benzodiazepines, and opioids (in 51.1 %, 38.1 %, and 17.2 % participants, respectively). More FRIDs were prescribed to the oldest old patients (85+) and participants from poorer regions of Croatia (Slavonia) (p < 0.05). Exposition to FRIDs was identified as the significant risk factor associated with falls (OR = 1.24 (1.04–1.50); p = 0.020) and higher health-care utilization (OR = 1.29 (1.10–1.51); p = 0.001). Our study highlights the need for rationalization of FRID use. To reduce the unnecessary exposure to FRIDs in older adults, health-care professionals must consider high individualization of medication schemes regarding selection, dosing, and combinations of only necessary FRIDs. |
| format | Article |
| id | doaj-art-524a64f275134d34ad8dd34a4e6587c3 |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-524a64f275134d34ad8dd34a4e6587c32025-02-02T15:47:25ZengSciendoActa Pharmaceutica1846-95582024-12-0174463565310.2478/acph-2024-0034Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 projectPaar Elizabeta0De Lai Eleonora1Držaić Margita2Kummer Ingrid3Bužančić Iva4Hadžiabdić Maja Ortner5Brkic Jovana6Fialová Daniela7University of Zagreb Faculty of Pharmacy and Biochemistry, Center for Applied Pharmacy, Zagreb, CroatiaUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Center for Applied Pharmacy, Zagreb, CroatiaUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Center for Applied Pharmacy, Zagreb, CroatiaCharles University, Faculty of Pharmacy, Department of Social and Clinical Pharmacy, Hradec KrálovéCzech RepublicUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Center for Applied Pharmacy, Zagreb, CroatiaUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Center for Applied Pharmacy, Zagreb, CroatiaCharles University, Faculty of Pharmacy, Department of Social and Clinical Pharmacy, Hradec KrálovéCzech RepublicCharles University, Faculty of Pharmacy, Department of Social and Clinical Pharmacy, Hradec KrálovéCzech RepublicOur study aimed to assess the prevalence of fall risk-increasing drugs (FRIDs) in a sample of community-residing older patients in Croatia and its association with negative health outcomes. An observational, cross-sectional study was conducted on older patients (65+) visiting community pharmacies in three regionally different study sites in Croatia. Data were collected using a questionnaire developed for that purpose and included components of comprehensive geriatric assessment. Prevalence of FRIDs was identified using the “Screening Tool of Older Persons Prescriptions in older adults with high fall risk” (STOPPFall). In the sample of 407 participants (median age 73 (IQR 69–70) years; 63.9 % females), 79.1 % used at least one FRID. The most common drug classes were diuretics, benzodiazepines, and opioids (in 51.1 %, 38.1 %, and 17.2 % participants, respectively). More FRIDs were prescribed to the oldest old patients (85+) and participants from poorer regions of Croatia (Slavonia) (p < 0.05). Exposition to FRIDs was identified as the significant risk factor associated with falls (OR = 1.24 (1.04–1.50); p = 0.020) and higher health-care utilization (OR = 1.29 (1.10–1.51); p = 0.001). Our study highlights the need for rationalization of FRID use. To reduce the unnecessary exposure to FRIDs in older adults, health-care professionals must consider high individualization of medication schemes regarding selection, dosing, and combinations of only necessary FRIDs.https://doi.org/10.2478/acph-2024-0034fall risk-increasing drugs (frids)older adultsstoppfallfalldeprescribing |
| spellingShingle | Paar Elizabeta De Lai Eleonora Držaić Margita Kummer Ingrid Bužančić Iva Hadžiabdić Maja Ortner Brkic Jovana Fialová Daniela Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project Acta Pharmaceutica fall risk-increasing drugs (frids) older adults stoppfall fall deprescribing |
| title | Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project |
| title_full | Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project |
| title_fullStr | Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project |
| title_full_unstemmed | Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project |
| title_short | Fall risk-increasing drugs and associated health outcomes among community-dwelling older patients: A cross-sectional study in Croatian cohort of the EuroAgeism H2020 project |
| title_sort | fall risk increasing drugs and associated health outcomes among community dwelling older patients a cross sectional study in croatian cohort of the euroageism h2020 project |
| topic | fall risk-increasing drugs (frids) older adults stoppfall fall deprescribing |
| url | https://doi.org/10.2478/acph-2024-0034 |
| work_keys_str_mv | AT paarelizabeta fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT delaieleonora fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT drzaicmargita fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT kummeringrid fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT buzanciciva fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT hadziabdicmajaortner fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT brkicjovana fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project AT fialovadaniela fallriskincreasingdrugsandassociatedhealthoutcomesamongcommunitydwellingolderpatientsacrosssectionalstudyincroatiancohortoftheeuroageismh2020project |