Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome

Membranoproliferative glomerulonephritis, one of the main causes of nephrotic syndrome, is associated with a state of hypercoagulability that leads to increased risk of thrombotic events. Portosystemic collaterals may reopen due to reversal of the flow within the existing veins and be a presenting f...

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Main Authors: Ilya Seleznev, Dinara Jumadilova, Assiya Naushabayeva, Kairat Kabulbayev, Gulaiym Karashasheva, Francesca Cainelli
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2019/3409832
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author Ilya Seleznev
Dinara Jumadilova
Assiya Naushabayeva
Kairat Kabulbayev
Gulaiym Karashasheva
Francesca Cainelli
author_facet Ilya Seleznev
Dinara Jumadilova
Assiya Naushabayeva
Kairat Kabulbayev
Gulaiym Karashasheva
Francesca Cainelli
author_sort Ilya Seleznev
collection DOAJ
description Membranoproliferative glomerulonephritis, one of the main causes of nephrotic syndrome, is associated with a state of hypercoagulability that leads to increased risk of thrombotic events. Portosystemic collaterals may reopen due to reversal of the flow within the existing veins and be a presenting feature of thrombosis. We describe a patient who presented with large portosystemic collaterals and signs of portal hypertension and was subsequently found to be affected by membranous proliferative glomerulonephritis. Proteinuria and microscopic haematuria in a patient with signs of portal hypertension and no pre-existing liver disease should raise the suspicion of an underlying kidney disease.
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institution Kabale University
issn 2090-6641
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language English
publishDate 2019-01-01
publisher Wiley
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series Case Reports in Nephrology
spelling doaj-art-52317981de7f40c7a504fdc03de0e91b2025-02-03T01:03:10ZengWileyCase Reports in Nephrology2090-66412090-665X2019-01-01201910.1155/2019/34098323409832Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic SyndromeIlya Seleznev0Dinara Jumadilova1Assiya Naushabayeva2Kairat Kabulbayev3Gulaiym Karashasheva4Francesca Cainelli5Department of Medicine, Nazarbayev University School of Medicine, Nur-Sultan, KazakhstanDepartment of Medicine, Nazarbayev University School of Medicine, Nur-Sultan, KazakhstanResearch Institute of Cardiology and Medicine, Almaty, KazakhstanResearch Institute of Cardiology and Medicine, Almaty, KazakhstanNational Scientific Center for Oncology and Transplantation, Nur-Sultan, KazakhstanDepartment of Medicine, Nazarbayev University School of Medicine, Nur-Sultan, KazakhstanMembranoproliferative glomerulonephritis, one of the main causes of nephrotic syndrome, is associated with a state of hypercoagulability that leads to increased risk of thrombotic events. Portosystemic collaterals may reopen due to reversal of the flow within the existing veins and be a presenting feature of thrombosis. We describe a patient who presented with large portosystemic collaterals and signs of portal hypertension and was subsequently found to be affected by membranous proliferative glomerulonephritis. Proteinuria and microscopic haematuria in a patient with signs of portal hypertension and no pre-existing liver disease should raise the suspicion of an underlying kidney disease.http://dx.doi.org/10.1155/2019/3409832
spellingShingle Ilya Seleznev
Dinara Jumadilova
Assiya Naushabayeva
Kairat Kabulbayev
Gulaiym Karashasheva
Francesca Cainelli
Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome
Case Reports in Nephrology
title Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome
title_full Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome
title_fullStr Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome
title_full_unstemmed Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome
title_short Portal Vein Thrombosis in a 21-Year-Old Man with Membranoproliferative Glomerulonephritis and Nephrotic Syndrome
title_sort portal vein thrombosis in a 21 year old man with membranoproliferative glomerulonephritis and nephrotic syndrome
url http://dx.doi.org/10.1155/2019/3409832
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