Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation
Liposomal bupivacaine has been explored for indications in regional anesthesia, but little has been reported about its use in pediatric patients. In March 2021, the FDA approved an indication for liposomal bupivacaine as an infiltrated local anesthetic in children older than the age of six. Despite...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2021/8092204 |
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| author | Gregory M. Halenda Stylianos Voulgarelis |
| author_facet | Gregory M. Halenda Stylianos Voulgarelis |
| author_sort | Gregory M. Halenda |
| collection | DOAJ |
| description | Liposomal bupivacaine has been explored for indications in regional anesthesia, but little has been reported about its use in pediatric patients. In March 2021, the FDA approved an indication for liposomal bupivacaine as an infiltrated local anesthetic in children older than the age of six. Despite this recently expanded indication, the literature lacks reports of use for peripheral nerve blockade in children. We describe a case where liposomal bupivacaine was used for femoral and sciatic nerve blocks in a 5-year-old child with traumatic amputation of his lower leg. Pain control was excellent, with no pain or opioid use reported during the first 62 hours. After the regional anesthesia subsided, the patient required in total 4 oral doses of oxycodone 0.1 mg/kg prior to discharge. The patient did not develop chronic pain or phantom limb syndrome. While liposomal bupivacaine is not currently FDA-approved for peripheral nerve blockade in children, this case highlights a potentially effective use of this drug and possible area for further investigation. |
| format | Article |
| id | doaj-art-51cd8b2446b140b9a2719b61e0a94ba0 |
| institution | Kabale University |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-51cd8b2446b140b9a2719b61e0a94ba02025-02-03T01:26:58ZengWileyCase Reports in Anesthesiology2090-63822090-63902021-01-01202110.1155/2021/80922048092204Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic AmputationGregory M. Halenda0Stylianos Voulgarelis1Department of Anesthesiology, Division of Pediatric Anesthesiology, Children’s of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin, USADepartment of Anesthesiology, Division of Pediatric Anesthesiology, Children’s of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin, USALiposomal bupivacaine has been explored for indications in regional anesthesia, but little has been reported about its use in pediatric patients. In March 2021, the FDA approved an indication for liposomal bupivacaine as an infiltrated local anesthetic in children older than the age of six. Despite this recently expanded indication, the literature lacks reports of use for peripheral nerve blockade in children. We describe a case where liposomal bupivacaine was used for femoral and sciatic nerve blocks in a 5-year-old child with traumatic amputation of his lower leg. Pain control was excellent, with no pain or opioid use reported during the first 62 hours. After the regional anesthesia subsided, the patient required in total 4 oral doses of oxycodone 0.1 mg/kg prior to discharge. The patient did not develop chronic pain or phantom limb syndrome. While liposomal bupivacaine is not currently FDA-approved for peripheral nerve blockade in children, this case highlights a potentially effective use of this drug and possible area for further investigation.http://dx.doi.org/10.1155/2021/8092204 |
| spellingShingle | Gregory M. Halenda Stylianos Voulgarelis Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation Case Reports in Anesthesiology |
| title | Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation |
| title_full | Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation |
| title_fullStr | Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation |
| title_full_unstemmed | Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation |
| title_short | Use of Liposomal Bupivacaine in Pediatric Peripheral Nerve Blocks after Traumatic Amputation |
| title_sort | use of liposomal bupivacaine in pediatric peripheral nerve blocks after traumatic amputation |
| url | http://dx.doi.org/10.1155/2021/8092204 |
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