Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes

We evaluated prevalence and clinical outcome of polyvascular disease (PolyVD) in patients presenting with acute coronary syndrome (ACS). Data for 7689 consecutive ACS patients were collected from the 2nd Gulf Registry of Acute Coronary Events between October 2008 and June 2009. Patients were divided...

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Main Authors: Hassan Al Thani, Ayman El-Menyar, Khalid F. AlHabib, Ahmed Al-Motarreb, Ahmad Hersi, Hussam AlFaleh, Nidal Asaad, Shukri Al Saif, Wael Almahmeed, Kadhim Sulaiman, Haitham Amin, Alawi A. Alsheikh-Ali, Khalid AlNemer, Jassim Al Suwaidi
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/284851
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author Hassan Al Thani
Ayman El-Menyar
Khalid F. AlHabib
Ahmed Al-Motarreb
Ahmad Hersi
Hussam AlFaleh
Nidal Asaad
Shukri Al Saif
Wael Almahmeed
Kadhim Sulaiman
Haitham Amin
Alawi A. Alsheikh-Ali
Khalid AlNemer
Jassim Al Suwaidi
author_facet Hassan Al Thani
Ayman El-Menyar
Khalid F. AlHabib
Ahmed Al-Motarreb
Ahmad Hersi
Hussam AlFaleh
Nidal Asaad
Shukri Al Saif
Wael Almahmeed
Kadhim Sulaiman
Haitham Amin
Alawi A. Alsheikh-Ali
Khalid AlNemer
Jassim Al Suwaidi
author_sort Hassan Al Thani
collection DOAJ
description We evaluated prevalence and clinical outcome of polyvascular disease (PolyVD) in patients presenting with acute coronary syndrome (ACS). Data for 7689 consecutive ACS patients were collected from the 2nd Gulf Registry of Acute Coronary Events between October 2008 and June 2009. Patients were divided into 2 groups (ACS with versus without PolyVD). All-cause mortality was assessed at 1 and 12 months. Patients with PolyVD were older and more likely to have cardiovascular risk factors. On presentation, those patients were more likely to have atypical angina, high resting heart rate, high Killip class, and GRACE risk scoring. They were less likely to receive evidence-based therapies. Diabetes mellitus, renal failure, and hypertension were independent predictors for presence of PolyVD. PolyVD was associated with worse in-hospital outcomes (except for major bleedings) and all-cause mortality even after adjusting for baseline covariates. Great efforts should be directed toward primary and secondary preventive measures.
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spelling doaj-art-51c7f2b512c346f884c295ae490fc08c2025-02-03T01:32:46ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/284851284851Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and OutcomesHassan Al Thani0Ayman El-Menyar1Khalid F. AlHabib2Ahmed Al-Motarreb3Ahmad Hersi4Hussam AlFaleh5Nidal Asaad6Shukri Al Saif7Wael Almahmeed8Kadhim Sulaiman9Haitham Amin10Alawi A. Alsheikh-Ali11Khalid AlNemer12Jassim Al Suwaidi13Department of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Doha 3050, QatarDepartment of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Doha 3050, QatarDepartment of Cardiology, King Fahad Cardiac Centre, College of Medicine, King Saud University, Riyadh 11472, Saudi ArabiaFaculty of Medicine, Sana’a University, Sana’a, YemenDepartment of Cardiology, King Fahad Cardiac Centre, College of Medicine, King Saud University, Riyadh 11472, Saudi ArabiaDepartment of Cardiology, King Fahad Cardiac Centre, College of Medicine, King Saud University, Riyadh 11472, Saudi ArabiaDepartment of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Doha 3050, QatarDepartment of Cardiology, Saud AllBabtain Cardiac Centre, Dammam 11850, Saudi ArabiaInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAEDepartment of Cardiology, Royal Hospital, Muscat, OmanMohammed Bin Khalifa Cardiac Centre, BahrainInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAEDepartment of Cardiology, Security Forces Hospital, Riyadh, Saudi ArabiaDepartment of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Doha 3050, QatarWe evaluated prevalence and clinical outcome of polyvascular disease (PolyVD) in patients presenting with acute coronary syndrome (ACS). Data for 7689 consecutive ACS patients were collected from the 2nd Gulf Registry of Acute Coronary Events between October 2008 and June 2009. Patients were divided into 2 groups (ACS with versus without PolyVD). All-cause mortality was assessed at 1 and 12 months. Patients with PolyVD were older and more likely to have cardiovascular risk factors. On presentation, those patients were more likely to have atypical angina, high resting heart rate, high Killip class, and GRACE risk scoring. They were less likely to receive evidence-based therapies. Diabetes mellitus, renal failure, and hypertension were independent predictors for presence of PolyVD. PolyVD was associated with worse in-hospital outcomes (except for major bleedings) and all-cause mortality even after adjusting for baseline covariates. Great efforts should be directed toward primary and secondary preventive measures.http://dx.doi.org/10.1100/2012/284851
spellingShingle Hassan Al Thani
Ayman El-Menyar
Khalid F. AlHabib
Ahmed Al-Motarreb
Ahmad Hersi
Hussam AlFaleh
Nidal Asaad
Shukri Al Saif
Wael Almahmeed
Kadhim Sulaiman
Haitham Amin
Alawi A. Alsheikh-Ali
Khalid AlNemer
Jassim Al Suwaidi
Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes
The Scientific World Journal
title Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes
title_full Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes
title_fullStr Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes
title_full_unstemmed Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes
title_short Polyvascular Disease in Patients Presenting with Acute Coronary Syndrome: Its Predictors and Outcomes
title_sort polyvascular disease in patients presenting with acute coronary syndrome its predictors and outcomes
url http://dx.doi.org/10.1100/2012/284851
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