The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta

The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta

Insulin-like growth factor 2 (IGF2) is essential for cell growth and differentiation and functions through the IGF2 receptor (IGF2R) to regulate embryonic and placental development. Exosomes that are synthesized and released from cells and play important roles in embryogenesis and placental developm...

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Main Authors: Kunhua ZHENG, Longfei XIAO, Naihan YUAN, Xihui SHENG, Xiaolong QI, Yingqiu WANG, Chang CHEN, Kaijun GUO, Lin YANG, Bingying LIU, Xiangguo WANG
Format: Article
Language:English
Published: The Society for Reproduction and Development 2024-12-01
Series:The Journal of Reproduction and Development
Subjects:
bovine
exosomes
insulin-like growth factor 2 (igf2)
insulin-like growth factor 2 receptor (igf2r)
placental trophoblast cells
Online Access:https://www.jstage.jst.go.jp/article/jrd/71/1/71_2024-081/_pdf/-char/en
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