Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum

Newly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical, especially in saving the consumption of serum material. Along with biochemical parameters, they have been successfully applied to diagnostics...

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Main Authors: Luterotti Svjetlana, Kordić Tončica Vukman, Letoja Ivka Zoričić, Dodig Slavica
Format: Article
Language:English
Published: Sciendo 2015-09-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2015-0027
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author Luterotti Svjetlana
Kordić Tončica Vukman
Letoja Ivka Zoričić
Dodig Slavica
author_facet Luterotti Svjetlana
Kordić Tončica Vukman
Letoja Ivka Zoričić
Dodig Slavica
author_sort Luterotti Svjetlana
collection DOAJ
description Newly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical, especially in saving the consumption of serum material. Along with biochemical parameters, they have been successfully applied to diagnostics/prognostics of tuberculosis in children, through analyses of sera from pediatric patients with lung tuberculosis or suspected tuberculosis, enabling the follow-up of therapeutic efficiency. The prognostic strength of Cu and Cu/Zn ratio together with C-reactive protein, complement components C3 and C4, and erythrocyte sedimentation rate have been documented.
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issn 1846-9558
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publishDate 2015-09-01
publisher Sciendo
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series Acta Pharmaceutica
spelling doaj-art-518e25d83e49487faca1ddbcf45124e32025-02-02T21:49:41ZengSciendoActa Pharmaceutica1846-95582015-09-0165332132910.1515/acph-2015-0027acph-2015-0027Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serumLuterotti Svjetlana0Kordić Tončica Vukman1Letoja Ivka Zoričić2Dodig Slavica3 Faculty of Pharmacy and Biochemistry, University of Zagreb, HR-10000 Zagreb, Croatia Agency for Medicinal Products and Medical Devices, HR-10000 Zagreb, Croatia Srebrnjak Children’s Hospital, HR-10000 Zagreb, Croatia Srebrnjak Children’s Hospital, HR-10000 Zagreb, CroatiaNewly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical, especially in saving the consumption of serum material. Along with biochemical parameters, they have been successfully applied to diagnostics/prognostics of tuberculosis in children, through analyses of sera from pediatric patients with lung tuberculosis or suspected tuberculosis, enabling the follow-up of therapeutic efficiency. The prognostic strength of Cu and Cu/Zn ratio together with C-reactive protein, complement components C3 and C4, and erythrocyte sedimentation rate have been documented.https://doi.org/10.1515/acph-2015-0027copperzinccu/zn ratiobiochemical parameterschildren’s serumlung tuberculosis
spellingShingle Luterotti Svjetlana
Kordić Tončica Vukman
Letoja Ivka Zoričić
Dodig Slavica
Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum
Acta Pharmaceutica
copper
zinc
cu/zn ratio
biochemical parameters
children’s serum
lung tuberculosis
title Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum
title_full Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum
title_fullStr Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum
title_full_unstemmed Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum
title_short Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum
title_sort contribution to diagnostics prognostics of tuberculosis in children ii indicative value of metal ions and biochemical parameters in serum
topic copper
zinc
cu/zn ratio
biochemical parameters
children’s serum
lung tuberculosis
url https://doi.org/10.1515/acph-2015-0027
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