The Impact of Surgery Delay on Early-Stage Ovarian Cancer
(1) Background: Suspicious adnexal masses should be referred to gynecological oncology units. However, when surgery waiting lists are prolonged, these patients usually suffer from a delay in surgery. This could have a negative impact on their prognosis when the final diagnosis is ovarian cancer (OC)...
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MDPI AG
2025-01-01
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| author | Dimitrios Zouzoulas Dimitrios Tsolakidis Iliana Sofianou Tilemachos Karalis Michalis Aristotelidis Panagiotis Tzitzis Evangelia Deligeoroglou Maria Topalidou Eleni Timotheadou Grigoris Grimbizis |
| author_facet | Dimitrios Zouzoulas Dimitrios Tsolakidis Iliana Sofianou Tilemachos Karalis Michalis Aristotelidis Panagiotis Tzitzis Evangelia Deligeoroglou Maria Topalidou Eleni Timotheadou Grigoris Grimbizis |
| author_sort | Dimitrios Zouzoulas |
| collection | DOAJ |
| description | (1) Background: Suspicious adnexal masses should be referred to gynecological oncology units. However, when surgery waiting lists are prolonged, these patients usually suffer from a delay in surgery. This could have a negative impact on their prognosis when the final diagnosis is ovarian cancer (OC). The primary aim of this study was to investigate the impact of surgery delay on the oncological results of early-stage ovarian cancer patients. (2) Methods: We retrospectively reviewed the records of early-stage OC patients who underwent surgery in the 1st Department of Obstetrics and Gynecology from 2012 to 2019. Time to surgery was defined as the time interval from the day of first examination to the day of surgery. (3) Results: A total of 72 patients were categorized into two groups, with a cut-off point of 5 weeks: 32 were treated ≤ 5 weeks (group A), and 40 > 5 weeks (group B). Concerning age, BMI or comorbidities, no differences were found between the two groups. Furthermore, no differences were presented in the post-operative complications rate, hospital stay, ICU admittance, or in disease-free (<i>p</i> = 0.48) and overall survival rates (<i>p</i> = 0.703). (4) Conclusions: Suspicious adnexal masses should undergo careful differential diagnosis to avoid delays in the “wait and see” period when the final diagnosis is positive for malignancy. However, the time to surgery for early-stage OC over 5 weeks seems to be relatively safe, with no impact on the mortality, morbidity, or recurrence rate. |
| format | Article |
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| institution | Kabale University |
| issn | 2075-1729 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj-art-518427ad499e460fac293e27c321dd262025-01-24T13:38:53ZengMDPI AGLife2075-17292025-01-0115112210.3390/life15010122The Impact of Surgery Delay on Early-Stage Ovarian CancerDimitrios Zouzoulas0Dimitrios Tsolakidis1Iliana Sofianou2Tilemachos Karalis3Michalis Aristotelidis4Panagiotis Tzitzis5Evangelia Deligeoroglou6Maria Topalidou7Eleni Timotheadou8Grigoris Grimbizis91st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, GreeceRadiotherapy Department, “Papageorgiou” Hospital, 564 29 Thessaloniki, GreeceDepartment of Oncology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, “Papageorgiou” Hospital, 564 29 Thessaloniki, Greece(1) Background: Suspicious adnexal masses should be referred to gynecological oncology units. However, when surgery waiting lists are prolonged, these patients usually suffer from a delay in surgery. This could have a negative impact on their prognosis when the final diagnosis is ovarian cancer (OC). The primary aim of this study was to investigate the impact of surgery delay on the oncological results of early-stage ovarian cancer patients. (2) Methods: We retrospectively reviewed the records of early-stage OC patients who underwent surgery in the 1st Department of Obstetrics and Gynecology from 2012 to 2019. Time to surgery was defined as the time interval from the day of first examination to the day of surgery. (3) Results: A total of 72 patients were categorized into two groups, with a cut-off point of 5 weeks: 32 were treated ≤ 5 weeks (group A), and 40 > 5 weeks (group B). Concerning age, BMI or comorbidities, no differences were found between the two groups. Furthermore, no differences were presented in the post-operative complications rate, hospital stay, ICU admittance, or in disease-free (<i>p</i> = 0.48) and overall survival rates (<i>p</i> = 0.703). (4) Conclusions: Suspicious adnexal masses should undergo careful differential diagnosis to avoid delays in the “wait and see” period when the final diagnosis is positive for malignancy. However, the time to surgery for early-stage OC over 5 weeks seems to be relatively safe, with no impact on the mortality, morbidity, or recurrence rate.https://www.mdpi.com/2075-1729/15/1/122surgery delayearly-stage ovarian cancerdiagnosisadnexal mass |
| spellingShingle | Dimitrios Zouzoulas Dimitrios Tsolakidis Iliana Sofianou Tilemachos Karalis Michalis Aristotelidis Panagiotis Tzitzis Evangelia Deligeoroglou Maria Topalidou Eleni Timotheadou Grigoris Grimbizis The Impact of Surgery Delay on Early-Stage Ovarian Cancer Life surgery delay early-stage ovarian cancer diagnosis adnexal mass |
| title | The Impact of Surgery Delay on Early-Stage Ovarian Cancer |
| title_full | The Impact of Surgery Delay on Early-Stage Ovarian Cancer |
| title_fullStr | The Impact of Surgery Delay on Early-Stage Ovarian Cancer |
| title_full_unstemmed | The Impact of Surgery Delay on Early-Stage Ovarian Cancer |
| title_short | The Impact of Surgery Delay on Early-Stage Ovarian Cancer |
| title_sort | impact of surgery delay on early stage ovarian cancer |
| topic | surgery delay early-stage ovarian cancer diagnosis adnexal mass |
| url | https://www.mdpi.com/2075-1729/15/1/122 |
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