New Derivatives of Oleanolic Acid: Semi-Synthesis and Evaluation of Their Anti-15-LOX, Anti-α-Glucosidase and Anticancer Activities and Molecular Docking Studies

New Derivatives of Oleanolic Acid: Semi-Synthesis and Evaluation of Their Anti-15-LOX, Anti-α-Glucosidase and Anticancer Activities and Molecular Docking Studies

A novel series of oleanolic acid (<b>OA</b>, <b>1</b>) derivatives incorporating phenolic and coumarin moieties were synthesized. This acid was extracted from olive pomace (<i>Olea europaea</i> L.) using an ultrasound-assisted method. The structures of these novel...

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Bibliographic Details
Main Authors: Nahla Triaa, Salma Jlizi, Mansour Znati, Hichem Ben Jannet, Jalloul Bouajila
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Chemistry
Subjects:
olive pomace
oleanolic acid
coumarin
phenolics
biological activities
docking studies
Online Access:https://www.mdpi.com/2624-8549/7/2/36
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