Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report

Neovascular glaucoma is a rare and serious condition typically associated with advanced ocular or systemic vascular diseases such as central retinal vein occlusion or diabetic retinopathy. This report describes a unique case of neovascular glaucoma presenting for the first time as an initial symptom...

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Main Authors: Klaudia Rakusiewicz-Krasnodębska, Joanna Jędrzejczak-Młodziejewska, Krystyna Kanigowska, Wojciech Hautz
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/1/148
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author Klaudia Rakusiewicz-Krasnodębska
Joanna Jędrzejczak-Młodziejewska
Krystyna Kanigowska
Wojciech Hautz
author_facet Klaudia Rakusiewicz-Krasnodębska
Joanna Jędrzejczak-Młodziejewska
Krystyna Kanigowska
Wojciech Hautz
author_sort Klaudia Rakusiewicz-Krasnodębska
collection DOAJ
description Neovascular glaucoma is a rare and serious condition typically associated with advanced ocular or systemic vascular diseases such as central retinal vein occlusion or diabetic retinopathy. This report describes a unique case of neovascular glaucoma presenting for the first time as an initial symptom of bilateral occlusive retinal vasculitis (ORV) in a generally healthy 4-year-old girl. The patient presented with symptoms of pain and redness in the left eye, accompanied by high intraocular pressure. These symptoms were particularly distressing and uncharacteristic for such a young child. Clinical examination revealed significant findings, including elevated intraocular pressure, corneal edema, and iris neovascularization in the left eye. Additional imaging studies, including fluorescein angiography, demonstrated extensive retinal ischemia with peripheral capillary nonperfusion, confirming the diagnosis of occlusive vasculitis. The management of this case was challenging due to the progressive and aggressive nature of the disease in a 4-year-old patient. This article aims to present the diagnostic and therapeutic strategies for the management of this condition. This report highlights a rare case of neovascular glaucoma as the first manifestation of bilateral ORV in a young child. The unusual presentation emphasizes the need for a high index of suspicion and comprehensive evaluation in cases of pediatric neovascular glaucoma. Early diagnosis and prompt, multimodal treatment are crucial in preventing irreversible vision loss in such cases.
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spelling doaj-art-514e8af888714d62b8924160be8f37ac2025-01-24T13:24:11ZengMDPI AGBiomedicines2227-90592025-01-0113114810.3390/biomedicines13010148Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case ReportKlaudia Rakusiewicz-Krasnodębska0Joanna Jędrzejczak-Młodziejewska1Krystyna Kanigowska2Wojciech Hautz3Department of the Pediatric Ophthalmology, Children’s Memorial Health Institute, 04-730 Warsaw, PolandDepartment of the Pediatric Ophthalmology, Children’s Memorial Health Institute, 04-730 Warsaw, PolandDepartment of the Pediatric Ophthalmology, Children’s Memorial Health Institute, 04-730 Warsaw, PolandDepartment of the Pediatric Ophthalmology, Children’s Memorial Health Institute, 04-730 Warsaw, PolandNeovascular glaucoma is a rare and serious condition typically associated with advanced ocular or systemic vascular diseases such as central retinal vein occlusion or diabetic retinopathy. This report describes a unique case of neovascular glaucoma presenting for the first time as an initial symptom of bilateral occlusive retinal vasculitis (ORV) in a generally healthy 4-year-old girl. The patient presented with symptoms of pain and redness in the left eye, accompanied by high intraocular pressure. These symptoms were particularly distressing and uncharacteristic for such a young child. Clinical examination revealed significant findings, including elevated intraocular pressure, corneal edema, and iris neovascularization in the left eye. Additional imaging studies, including fluorescein angiography, demonstrated extensive retinal ischemia with peripheral capillary nonperfusion, confirming the diagnosis of occlusive vasculitis. The management of this case was challenging due to the progressive and aggressive nature of the disease in a 4-year-old patient. This article aims to present the diagnostic and therapeutic strategies for the management of this condition. This report highlights a rare case of neovascular glaucoma as the first manifestation of bilateral ORV in a young child. The unusual presentation emphasizes the need for a high index of suspicion and comprehensive evaluation in cases of pediatric neovascular glaucoma. Early diagnosis and prompt, multimodal treatment are crucial in preventing irreversible vision loss in such cases.https://www.mdpi.com/2227-9059/13/1/148neovascular glaucomapediatric ophthalmologyocclusive retinal vasculitis (ORV)retinal ischemiaanti-vascular endothelial growth factor therapy
spellingShingle Klaudia Rakusiewicz-Krasnodębska
Joanna Jędrzejczak-Młodziejewska
Krystyna Kanigowska
Wojciech Hautz
Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report
Biomedicines
neovascular glaucoma
pediatric ophthalmology
occlusive retinal vasculitis (ORV)
retinal ischemia
anti-vascular endothelial growth factor therapy
title Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report
title_full Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report
title_fullStr Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report
title_full_unstemmed Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report
title_short Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report
title_sort neovascular glaucoma as the first symptom of bilateral occlusive retinal vasculitis in a 4 year old girl a case report
topic neovascular glaucoma
pediatric ophthalmology
occlusive retinal vasculitis (ORV)
retinal ischemia
anti-vascular endothelial growth factor therapy
url https://www.mdpi.com/2227-9059/13/1/148
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AT krystynakanigowska neovascularglaucomaasthefirstsymptomofbilateralocclusiveretinalvasculitisina4yearoldgirlacasereport
AT wojciechhautz neovascularglaucomaasthefirstsymptomofbilateralocclusiveretinalvasculitisina4yearoldgirlacasereport