Evaluation of the microenvironment formed by interferon-β

Evaluation of the microenvironment formed by interferon-β

Heterogeneity in the cellular microenvironment in vivo affects the variability of reactivity among immune cells. Individual-specific microenvironmental differences play a crucial role in determining macroscopic outcomes, such as the efficacy of immunotherapy and disease progression. The microenviron...

Full description

Saved in:

Bibliographic Details
Main Authors:	Mai Yamagishi, Yutaka Hori, Nobutake Suzuki, Yu Peng, Yoshie Harada, Takashi Funatsu, Osamu Ohara, Yoshitaka Shirasaki
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Chemical Biology
Subjects:	cytokine microenvironment live-cell imaging heterogeneity immune response IFN-β
Online Access:	https://www.frontiersin.org/articles/10.3389/fchbi.2024.1425571/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Microdifferential Pressure Measurement Device for Cellular Microenvironments
by: Mami Akaike, et al.
Published: (2024-12-01)

Response Gene to Complement 32 is associated with poor patient survival and an inflamed tumor-immune microenvironment in clear cell renal cell carcinoma
by: Lingling Li, et al.
Published: (2025-02-01)

Successful treatment of life-threatening mycobacteriosis using adjunctive gamma-interferon therapy with genetic analysis
by: P. Confalonieri, et al.
Published: (2024-01-01)

Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing
by: Jingyuan Huo, et al.
Published: (2024-12-01)

The concerted actions of microRNA-29a and interferon-β modulate complete Freund's adjuvant-induced inflammatory pain by regulating the expression of type 1 interferon receptor, interferon-stimulated gene 15, and p-extracellular signal-regulated kinase
by: Chien-Cheng Liu, et al.
Published: (2025-03-01)

Optimized production and antiviral activity evaluation of recombinant chicken interferon-alpha using an improved Baculovirus expression system
by: Yuxia Zhang, et al.
Published: (2025-03-01)

HDAC6 Facilitates PRV and VSV Infection by Inhibiting Type I Interferon Production
by: Hu Zheng, et al.
Published: (2025-01-01)

Editorial: Activation of the cGAS-STING pathway by extra-nuclear DNA and its pharmacognostic modulation in human disease
by: Preston M. McCourt, et al.
Published: (2025-01-01)

Comprehensive single-cell atlas of colorectal neuroendocrine tumors with liver metastases: unraveling tumor microenvironment heterogeneity between primary lesions and metastases
by: Yiqiao Deng, et al.
Published: (2025-01-01)

Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons
by: Huizi Li, et al.
Published: (2025-03-01)

Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer
by: Yaojun Ren, et al.
Published: (2025-02-01)

The effect of interferon alpha administration on cytokine levels in sheep
by: Devran Coşkun, et al.
Published: (2020-12-01)

Tumor cells proliferation and migration under the influence of their microenvironment
by: Avner Friedman, et al.
Published: (2011-03-01)

Role of nasal microbiota in regulating host anti-influenza immunity in dogs
by: Jinzhu Geng, et al.
Published: (2025-01-01)

Immunotherapy of osteosarcoma based on immune microenvironment modulation
by: Heping Lian, et al.
Published: (2025-01-01)

Frk positively regulates innate antiviral immunity by phosphorylating TBK1
by: Xiaomei Zhang, et al.
Published: (2025-02-01)

Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression
by: Shankar Suman, et al.
Published: (2025-01-01)

Prostate Cancer Bone Metastasis: Molecular Mechanisms of Tumor and Bone Microenvironment
by: Jiang H
Published: (2025-02-01)

Cryo-thermal therapy reshaped the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy
by: Shicheng Wang, et al.
Published: (2024-11-01)

Dissecting macrophage heterogeneity and kaempferol in lung adenocarcinoma: a single-cell transcriptomic approach and network pharmacology
by: Laiyi Wan, et al.
Published: (2025-01-01)

Tumor microenvironment-responsive hyperbranched polymers for controlled drug delivery
by: Yuqiong Guo, et al.
Published: (2024-12-01)

Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
by: Kira A Cozzolino, et al.
Published: (2025-02-01)

Optimizing Microneutralization and IFN-γ ELISPOT Assays to Evaluate Mpox Immunity
by: Yinyi Yu, et al.
Published: (2024-12-01)

Impact of HIF-1α, LOX and ITGA5 Synergistic Interaction in the Tumor Microenvironment on Colorectal Cancer Prognosis
by: Hayriye Tatlı Doğan, et al.
Published: (2025-01-01)

The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer
by: Si Chen, et al.
Published: (2024-09-01)

DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge
by: Victoria Gnazzo, et al.
Published: (2025-02-01)

Agent-based modeling for the tumor microenvironment (TME)
by: Hasitha N. Weerasinghe, et al.
Published: (2024-11-01)

Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
by: Yuyun Zhong, et al.
Published: (2025-01-01)

Lactate accumulation promotes immunosuppression and fibrotic transformation of bone marrow microenvironment in myelofibrosis
by: Mariarita Spampinato, et al.
Published: (2025-01-01)

Therapeutic implications and comprehensive insights into cellular senescence and aging in the tumor microenvironment of sarcoma
by: Pengfei Zan, et al.
Published: (2025-01-01)

The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy
by: Qinglong Ma, et al.
Published: (2025-01-01)

Deciphering mechanical cues in the microenvironment: from non-malignant settings to tumor progression
by: Yicheng Zhu, et al.
Published: (2025-01-01)

Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer
by: Soomin Kim, et al.
Published: (2025-02-01)

The colorectal cancer microenvironment: Preclinical progress in identifying targets for cancer therapy
by: Abdo Meyiah, et al.
Published: (2025-03-01)

Evaluating Ultrafine Particles and PM2.5 in Microenvironments with Health Perspectives: Variability in Concentrations and Pollutant Interrelationships
by: Sheng Xiang, et al.
Published: (2023-07-01)

Predicting immunotherapy efficacy in endometrial cancer: focus on the tumor microenvironment
by: Liubov A. Tashireva, et al.
Published: (2025-01-01)

Harnessing nanoparticles for reshaping tumor immune microenvironment of hepatocellular carcinoma
by: JinSong Li, et al.
Published: (2025-02-01)

A Potential Role of MicroRNA in the Renal Cancer and Its Tumor Microenvironment
by: Daniel Chikere Ali, et al.
Published: (2025-01-01)

Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer
by: Yi Xie, et al.
Published: (2025-02-01)

Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment
by: Liang Peng, et al.
Published: (2025-02-01)