Subretinal suspensions of hiPSC-derived retinal pigment epithelium cells form functional monolayers in NOD-SCID mice facilitating treatment of advanced retinal diseases

Subretinal suspensions of hiPSC-derived retinal pigment epithelium cells form functional monolayers in NOD-SCID mice facilitating treatment of advanced retinal diseases

Introduction: Transplantation of human induced pluripotent stem cells derived retinal pigment epithelium (hiPSC-RPE) is regarded as one of the most promising strategies for advanced retinal degenerative diseases leading to blindness, such as age-related macular degeneration. Despite its therapeutic...

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Bibliographic Details
Main Authors:	Xiaojing Song, Guanjie Gao, Ke Ye, Ping Xu, Yuan Wang, Suai Zhang, Dandan Zheng, Jian Ge, Xiufeng Zhong
Format:	Article
Language:	English
Published:	Elsevier 2025-12-01
Series:	Regenerative Therapy
Subjects:	Cell therapy Human induced pluripotent stem cells Retinal pigment epithelium Monolayer Age-related macular degeneration
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352320425001543
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