Tolosa-Hunt Syndrome in Double-Hit Lymphoma

Tolosa-Hunt syndrome (THS) is a painful condition characterized by hemicranial pain, retroorbital pain, loss of vision, oculomotor nerve paralysis, and sensory loss in distribution of ophthalmic and maxillary division of trigeminal nerve. Lymphomas rarely involve cavernous sinus and simulate Tolosa-...

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Main Authors: Prakash Peddi, Kevin M. Gallagher, Chandrikha Chandrasekharan, Qi Wang, Eduardo Gonzalez-Toledo, Binu S. Nair, Reinhold Munker, Glenn M. Mills, Nebu V. Koshy
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2015/249891
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author Prakash Peddi
Kevin M. Gallagher
Chandrikha Chandrasekharan
Qi Wang
Eduardo Gonzalez-Toledo
Binu S. Nair
Reinhold Munker
Glenn M. Mills
Nebu V. Koshy
author_facet Prakash Peddi
Kevin M. Gallagher
Chandrikha Chandrasekharan
Qi Wang
Eduardo Gonzalez-Toledo
Binu S. Nair
Reinhold Munker
Glenn M. Mills
Nebu V. Koshy
author_sort Prakash Peddi
collection DOAJ
description Tolosa-Hunt syndrome (THS) is a painful condition characterized by hemicranial pain, retroorbital pain, loss of vision, oculomotor nerve paralysis, and sensory loss in distribution of ophthalmic and maxillary division of trigeminal nerve. Lymphomas rarely involve cavernous sinus and simulate Tolosa-Hunt syndrome. Here we present a first case of double-hit B cell lymphoma (DHL) relapsing and masquerading as Tolosa-Hunt syndrome. The neurological findings were explained by a lymphomatous infiltration of the right Gasserian ganglion which preceded systemic relapse. As part of this report, the diagnostic criteria for Tolosa-Hunt syndrome and double-hit lymphoma are reviewed and updated treatment recommendations are presented.
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institution Kabale University
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publishDate 2015-01-01
publisher Wiley
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series Case Reports in Oncological Medicine
spelling doaj-art-513083012be34ca9ac6e5b26b664d5be2025-02-03T06:07:20ZengWileyCase Reports in Oncological Medicine2090-67062090-67142015-01-01201510.1155/2015/249891249891Tolosa-Hunt Syndrome in Double-Hit LymphomaPrakash Peddi0Kevin M. Gallagher1Chandrikha Chandrasekharan2Qi Wang3Eduardo Gonzalez-Toledo4Binu S. Nair5Reinhold Munker6Glenn M. Mills7Nebu V. Koshy8Department of Medicine, Section of Hematology and Oncology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Medicine, Section of Hematology and Oncology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Medicine, Section of Hematology and Oncology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Pathology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Radiology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Medicine, Section of Hematology and Oncology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Medicine, Section of Hematology and Oncology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Medicine, Section of Hematology and Oncology, Louisiana State University Health, Shreveport, LA 71103, USADepartment of Medicine, Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY 10065, USATolosa-Hunt syndrome (THS) is a painful condition characterized by hemicranial pain, retroorbital pain, loss of vision, oculomotor nerve paralysis, and sensory loss in distribution of ophthalmic and maxillary division of trigeminal nerve. Lymphomas rarely involve cavernous sinus and simulate Tolosa-Hunt syndrome. Here we present a first case of double-hit B cell lymphoma (DHL) relapsing and masquerading as Tolosa-Hunt syndrome. The neurological findings were explained by a lymphomatous infiltration of the right Gasserian ganglion which preceded systemic relapse. As part of this report, the diagnostic criteria for Tolosa-Hunt syndrome and double-hit lymphoma are reviewed and updated treatment recommendations are presented.http://dx.doi.org/10.1155/2015/249891
spellingShingle Prakash Peddi
Kevin M. Gallagher
Chandrikha Chandrasekharan
Qi Wang
Eduardo Gonzalez-Toledo
Binu S. Nair
Reinhold Munker
Glenn M. Mills
Nebu V. Koshy
Tolosa-Hunt Syndrome in Double-Hit Lymphoma
Case Reports in Oncological Medicine
title Tolosa-Hunt Syndrome in Double-Hit Lymphoma
title_full Tolosa-Hunt Syndrome in Double-Hit Lymphoma
title_fullStr Tolosa-Hunt Syndrome in Double-Hit Lymphoma
title_full_unstemmed Tolosa-Hunt Syndrome in Double-Hit Lymphoma
title_short Tolosa-Hunt Syndrome in Double-Hit Lymphoma
title_sort tolosa hunt syndrome in double hit lymphoma
url http://dx.doi.org/10.1155/2015/249891
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