SFannotation: A Simple and Fast Protein Function Annotation System
Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a...
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| Format: | Article |
| Language: | English |
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BioMed Central
2014-06-01
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| Series: | Genomics & Informatics |
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| Online Access: | http://genominfo.org/upload/pdf/gni-12-76.pdf |
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| _version_ | 1832570769083727872 |
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| author | Dong Su Yu Byung Kwon Kim |
| author_facet | Dong Su Yu Byung Kwon Kim |
| author_sort | Dong Su Yu |
| collection | DOAJ |
| description | Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a functional annotation system that uses extant databases, but the expansive size of these databases often causes a bottleneck for rapid functional annotation. We developed SFannotation, a simple and fast functional annotation system that rapidly annotates putative proteins against four extant databases, Swiss-Prot, TIGRFAMs, Pfam, and the non-redundant sequence database, by using a best-hit approach with BLASTP and HMMSEARCH. |
| format | Article |
| id | doaj-art-510eccdcab7b41298c374c67278ea154 |
| institution | Kabale University |
| issn | 1598-866X 2234-0742 |
| language | English |
| publishDate | 2014-06-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-510eccdcab7b41298c374c67278ea1542025-02-02T14:17:56ZengBioMed CentralGenomics & Informatics1598-866X2234-07422014-06-01122767810.5808/GI.2014.12.2.76128SFannotation: A Simple and Fast Protein Function Annotation SystemDong Su Yu0Byung Kwon Kim1Korean BioInformation Center (KOBIC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea.BioNano Health Guard Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea.Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a functional annotation system that uses extant databases, but the expansive size of these databases often causes a bottleneck for rapid functional annotation. We developed SFannotation, a simple and fast functional annotation system that rapidly annotates putative proteins against four extant databases, Swiss-Prot, TIGRFAMs, Pfam, and the non-redundant sequence database, by using a best-hit approach with BLASTP and HMMSEARCH.http://genominfo.org/upload/pdf/gni-12-76.pdfbioinformaticsgene productprotein annotation |
| spellingShingle | Dong Su Yu Byung Kwon Kim SFannotation: A Simple and Fast Protein Function Annotation System Genomics & Informatics bioinformatics gene product protein annotation |
| title | SFannotation: A Simple and Fast Protein Function Annotation System |
| title_full | SFannotation: A Simple and Fast Protein Function Annotation System |
| title_fullStr | SFannotation: A Simple and Fast Protein Function Annotation System |
| title_full_unstemmed | SFannotation: A Simple and Fast Protein Function Annotation System |
| title_short | SFannotation: A Simple and Fast Protein Function Annotation System |
| title_sort | sfannotation a simple and fast protein function annotation system |
| topic | bioinformatics gene product protein annotation |
| url | http://genominfo.org/upload/pdf/gni-12-76.pdf |
| work_keys_str_mv | AT dongsuyu sfannotationasimpleandfastproteinfunctionannotationsystem AT byungkwonkim sfannotationasimpleandfastproteinfunctionannotationsystem |