Biomaterial-based drug delivery systems in the treatment of inner ear disorders

Biomaterial-based drug delivery systems in the treatment of inner ear disorders

Abstract Inner ear disorders are among the predominant etiology of hearing loss. The blood-labyrinth barrier limits the ability of drugs to attain pharmacologically effective concentrations within the inner ear; consequently, delivering drugs systemically is insufficient for effectively treating inn...

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Bibliographic Details
Main Authors: Hong Cheng, Bin Zhang, Pei Jiang, Menghui Liao, Xin Gao, Dongyu Xu, Yusong Wang, Yangnan Hu, Huan Wang, Tingting Liu, Renjie Chai
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Nanobiotechnology
Subjects:
Drug delivery
Inner ear disorders
Hearing loss
Biomaterials
Online Access:https://doi.org/10.1186/s12951-025-03368-0
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