Spirochetes in the Liver: An Unusual Presentation of a Common STI

It is estimated that 10% of patients with secondary syphilis have liver enzyme elevations, but clinical hepatitis is rare. However, in HIV-positive patients, syphilitic hepatitis may be much more common. We report a case of a 67-year-old male who developed progressively elevated liver enzymes, follo...

Full description

Saved in:
Bibliographic Details
Main Authors: Natasha Narang, Layth Al-Jashaami, Nayan Patel
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2019/1012405
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832563770899038208
author Natasha Narang
Layth Al-Jashaami
Nayan Patel
author_facet Natasha Narang
Layth Al-Jashaami
Nayan Patel
author_sort Natasha Narang
collection DOAJ
description It is estimated that 10% of patients with secondary syphilis have liver enzyme elevations, but clinical hepatitis is rare. However, in HIV-positive patients, syphilitic hepatitis may be much more common. We report a case of a 67-year-old male who developed progressively elevated liver enzymes, followed by development of neurological symptoms and then rash. Though the timeline of his symptom development was unusual, his constellation of symptoms prompted an RPR and FTA-ABS which returned reactive. He was additionally found to be HIV positive with a CD4 count of 946. He was treated with IV Penicillin, and his hepatitis improved thereafter.
format Article
id doaj-art-50e374a9fcd64ee4a1e9b5d33cf90ecf
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-50e374a9fcd64ee4a1e9b5d33cf90ecf2025-02-03T01:12:34ZengWileyCase Reports in Medicine1687-96271687-96352019-01-01201910.1155/2019/10124051012405Spirochetes in the Liver: An Unusual Presentation of a Common STINatasha Narang0Layth Al-Jashaami1Nayan Patel2Department of Internal Medicine, Banner University Medical Center, Phoenix, AZ, USADepartment of Gastroenterology, Banner University Medical Center, Phoenix, AZ, USADepartment of Gastroenterology, Banner University Medical Center, Phoenix, AZ, USAIt is estimated that 10% of patients with secondary syphilis have liver enzyme elevations, but clinical hepatitis is rare. However, in HIV-positive patients, syphilitic hepatitis may be much more common. We report a case of a 67-year-old male who developed progressively elevated liver enzymes, followed by development of neurological symptoms and then rash. Though the timeline of his symptom development was unusual, his constellation of symptoms prompted an RPR and FTA-ABS which returned reactive. He was additionally found to be HIV positive with a CD4 count of 946. He was treated with IV Penicillin, and his hepatitis improved thereafter.http://dx.doi.org/10.1155/2019/1012405
spellingShingle Natasha Narang
Layth Al-Jashaami
Nayan Patel
Spirochetes in the Liver: An Unusual Presentation of a Common STI
Case Reports in Medicine
title Spirochetes in the Liver: An Unusual Presentation of a Common STI
title_full Spirochetes in the Liver: An Unusual Presentation of a Common STI
title_fullStr Spirochetes in the Liver: An Unusual Presentation of a Common STI
title_full_unstemmed Spirochetes in the Liver: An Unusual Presentation of a Common STI
title_short Spirochetes in the Liver: An Unusual Presentation of a Common STI
title_sort spirochetes in the liver an unusual presentation of a common sti
url http://dx.doi.org/10.1155/2019/1012405
work_keys_str_mv AT natashanarang spirochetesintheliveranunusualpresentationofacommonsti
AT laythaljashaami spirochetesintheliveranunusualpresentationofacommonsti
AT nayanpatel spirochetesintheliveranunusualpresentationofacommonsti