Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations
A simple and reproducible spectrophotometric method has been developed for the determination of Ziprasidone hydrochloride monohydrate (ZPS) in bulk and in dosage forms. The method is based on the extraction of the drugs into organic layer of the dye TPooo in presence of 0.1 N hydrochloric acid and t...
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2006/643624 |
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| _version_ | 1832548053357166592 |
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| author | G. Srinubabu B. Sudha Rani J. V. L. N. Seshagiri Rao |
| author_facet | G. Srinubabu B. Sudha Rani J. V. L. N. Seshagiri Rao |
| author_sort | G. Srinubabu |
| collection | DOAJ |
| description | A simple and reproducible spectrophotometric method has been developed for the determination of Ziprasidone hydrochloride monohydrate (ZPS) in bulk and in dosage forms. The method is based on the extraction of the drugs into organic layer of the dye TPooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 490 nm. Results indicate that the proposed method was simple, sensitive, accurate and reproducible. |
| format | Article |
| id | doaj-art-50df28bbf4354134b6983e4820abe9e6 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-50df28bbf4354134b6983e4820abe9e62025-02-03T06:42:19ZengWileyE-Journal of Chemistry0973-49452090-98102006-01-013191210.1155/2006/643624Spectrophotometric Determination of Ziprasidone in Pharmaceutical FormulationsG. Srinubabu0B. Sudha Rani1J. V. L. N. Seshagiri Rao2University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam–530003, (A.P.), IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Visakhapatnam–530003, (A.P.), IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Visakhapatnam–530003, (A.P.), IndiaA simple and reproducible spectrophotometric method has been developed for the determination of Ziprasidone hydrochloride monohydrate (ZPS) in bulk and in dosage forms. The method is based on the extraction of the drugs into organic layer of the dye TPooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 490 nm. Results indicate that the proposed method was simple, sensitive, accurate and reproducible.http://dx.doi.org/10.1155/2006/643624 |
| spellingShingle | G. Srinubabu B. Sudha Rani J. V. L. N. Seshagiri Rao Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations E-Journal of Chemistry |
| title | Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations |
| title_full | Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations |
| title_fullStr | Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations |
| title_full_unstemmed | Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations |
| title_short | Spectrophotometric Determination of Ziprasidone in Pharmaceutical Formulations |
| title_sort | spectrophotometric determination of ziprasidone in pharmaceutical formulations |
| url | http://dx.doi.org/10.1155/2006/643624 |
| work_keys_str_mv | AT gsrinubabu spectrophotometricdeterminationofziprasidoneinpharmaceuticalformulations AT bsudharani spectrophotometricdeterminationofziprasidoneinpharmaceuticalformulations AT jvlnseshagirirao spectrophotometricdeterminationofziprasidoneinpharmaceuticalformulations |