NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

Summary: Background: Nuclear factor kappa B (NF-κB) c-Rel is a psoriasis susceptibility locus, however mechanisms underlying c-Rel transactivation during disease are poorly understood. Inflammation in psoriasis can be triggered following Toll-like Receptor 7 (TLR7) signalling in dendritic cells (DC...

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Bibliographic Details
Main Authors: Angela Rose Liu, Nandini Sarkar, Jordan D. Cress, Tristan J. de Jesus, Ananya Vadlakonda, Joshua T. Centore, Alexis D. Griffith, Bethany Rohr, Thomas S. McCormick, Kevin D. Cooper, Parameswaran Ramakrishnan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:EBioMedicine
Subjects:
TLR7
NF-κB c-Rel
Inflammation
Psoriasis
Transcription
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004882
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