Combined effects of global DNA methylation, blood lead and total urinary arsenic levels on developmental delay in preschool children

Combined effects of global DNA methylation, blood lead and total urinary arsenic levels on developmental delay in preschool children

Abstract DNA methylation is a critical step in brain development, 5-Methyl-2'-deoxycytidine (5mdC) is one of the global DNA methylation markers. Arsenic and lead exposures have been associated with neurotoxicity, which may be linked to epigenetic changes. Our research sought to investigate the...

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Main Authors: Yuu-Hueih Hsu, Chih-Yin Wu, Hui-Ling Lee, Ru-Lan Hsieh, Ya-Li Huang, Horng-Sheng Shiue, Ying-Chin Lin, Mei-Chieh Chen, Yu-Mei Hsueh
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Environmental Health
Subjects:
5-methyl-2’-deoxycytidine
Arsenic
Lead
Developmental delay
Preschool children
Online Access:https://doi.org/10.1186/s12940-024-01151-6
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