Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study

Objectives. Sessile nonampullary duodenal tumors (SNADTs) are relatively rare and endoscopic resection of these lesions is considered more challenging than in other parts of the gastrointestinal tract. The aim of this study was to evaluate the feasibility of endoscopic resection for SNADT. Methods....

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Main Authors: Sung Min Park, Joo Ho Ham, Byung-Wook Kim, Joon Sung Kim, Chang Whan Kim, Jin Il Kim, Chul Hyun Lim, Jung Hwan Oh
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/692492
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author Sung Min Park
Joo Ho Ham
Byung-Wook Kim
Joon Sung Kim
Chang Whan Kim
Jin Il Kim
Chul Hyun Lim
Jung Hwan Oh
author_facet Sung Min Park
Joo Ho Ham
Byung-Wook Kim
Joon Sung Kim
Chang Whan Kim
Jin Il Kim
Chul Hyun Lim
Jung Hwan Oh
author_sort Sung Min Park
collection DOAJ
description Objectives. Sessile nonampullary duodenal tumors (SNADTs) are relatively rare and endoscopic resection of these lesions is considered more challenging than in other parts of the gastrointestinal tract. The aim of this study was to evaluate the feasibility of endoscopic resection for SNADT. Methods. Medical records including endoscopic resection for SNADT from July 2002 to July 2013 from 5 centers affiliated to The Catholic University of Korea were reviewed retrospectively. Demographic features and clinical outcomes such as complete resection and complications were analyzed. Results. A total of 56 lesions from 54 patients were enrolled in this study. Forty-five lesions were resected by endoscopic mucosal resection (EMR), 6 lesions by endoscopic submucosal dissection (ESD), and 5 lesions by simple polypectomy. Histologic examination after endoscopic resection revealed adenocarcinoma in 2, low grade adenoma in 25, high grade adenoma in 11, and carcinoid tumor in 18 lesions. En bloc resection rates and histological complete resection rates were 78.6% (44/56) and 80.0% (28/35), respectively. Bleeding which required additional endoscopic intervention occurred in 1.8% (1/56) and perforation in 7.1% (4/56). There was no procedure-related mortality. Conclusions. Endoscopic resection techniques including ESD might be safe and effective modalities for the management of SNADT.
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spelling doaj-art-50673f83b27344929be159e942f1e5742025-08-20T02:05:10ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/692492692492Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective StudySung Min Park0Joo Ho Ham1Byung-Wook Kim2Joon Sung Kim3Chang Whan Kim4Jin Il Kim5Chul Hyun Lim6Jung Hwan Oh7Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaDivision of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaBucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaYeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaSeoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaSt. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 403-720, Republic of KoreaObjectives. Sessile nonampullary duodenal tumors (SNADTs) are relatively rare and endoscopic resection of these lesions is considered more challenging than in other parts of the gastrointestinal tract. The aim of this study was to evaluate the feasibility of endoscopic resection for SNADT. Methods. Medical records including endoscopic resection for SNADT from July 2002 to July 2013 from 5 centers affiliated to The Catholic University of Korea were reviewed retrospectively. Demographic features and clinical outcomes such as complete resection and complications were analyzed. Results. A total of 56 lesions from 54 patients were enrolled in this study. Forty-five lesions were resected by endoscopic mucosal resection (EMR), 6 lesions by endoscopic submucosal dissection (ESD), and 5 lesions by simple polypectomy. Histologic examination after endoscopic resection revealed adenocarcinoma in 2, low grade adenoma in 25, high grade adenoma in 11, and carcinoid tumor in 18 lesions. En bloc resection rates and histological complete resection rates were 78.6% (44/56) and 80.0% (28/35), respectively. Bleeding which required additional endoscopic intervention occurred in 1.8% (1/56) and perforation in 7.1% (4/56). There was no procedure-related mortality. Conclusions. Endoscopic resection techniques including ESD might be safe and effective modalities for the management of SNADT.http://dx.doi.org/10.1155/2015/692492
spellingShingle Sung Min Park
Joo Ho Ham
Byung-Wook Kim
Joon Sung Kim
Chang Whan Kim
Jin Il Kim
Chul Hyun Lim
Jung Hwan Oh
Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study
Gastroenterology Research and Practice
title Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study
title_full Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study
title_fullStr Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study
title_full_unstemmed Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study
title_short Feasibility of Endoscopic Resection for Sessile Nonampullary Duodenal Tumors: A Multicenter Retrospective Study
title_sort feasibility of endoscopic resection for sessile nonampullary duodenal tumors a multicenter retrospective study
url http://dx.doi.org/10.1155/2015/692492
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