Determination of Senegenin and Tenuifolin in Mouse Blood by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry and Their Pharmacokinetics

Determination of Senegenin and Tenuifolin in Mouse Blood by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry and Their Pharmacokinetics

An ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the determination of senegenin and tenuifolin in mouse blood was developed. The pharmacokinetics of senegenin and tenuifolin in mice after intravenous (5 mg/kg) and oral (60 mg/kg) administration were st...

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Bibliographic Details
Main Authors:	Xiuwei Shen, Xiangyi Dai, Yifan He, Congcong Wen, Qingwei Zhang
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	International Journal of Analytical Chemistry
Online Access:	http://dx.doi.org/10.1155/2022/3401355
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