Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders

Abstract Background Despite widespread use of higher levels of care in treating eating disorders in adolescents, research supporting the use of these treatments remains limited by small sample sizes and a predominant focus on anorexia nervosa. Further, existing data regarding predictors of outcome h...

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Main Authors: Erin E. Reilly, Sasha Gorrell, Alan Duffy, Dan V. Blalock, Philip Mehler, Harry Brandt, Susan McClanahan, Kianna Zucker, Naomi Lynch, Simar Singh, Catherine R. Drury, Daniel Le Grange, Renee D. Rienecke
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Child and Adolescent Psychiatry and Mental Health
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Online Access:https://doi.org/10.1186/s13034-024-00819-8
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author Erin E. Reilly
Sasha Gorrell
Alan Duffy
Dan V. Blalock
Philip Mehler
Harry Brandt
Susan McClanahan
Kianna Zucker
Naomi Lynch
Simar Singh
Catherine R. Drury
Daniel Le Grange
Renee D. Rienecke
author_facet Erin E. Reilly
Sasha Gorrell
Alan Duffy
Dan V. Blalock
Philip Mehler
Harry Brandt
Susan McClanahan
Kianna Zucker
Naomi Lynch
Simar Singh
Catherine R. Drury
Daniel Le Grange
Renee D. Rienecke
author_sort Erin E. Reilly
collection DOAJ
description Abstract Background Despite widespread use of higher levels of care in treating eating disorders in adolescents, research supporting the use of these treatments remains limited by small sample sizes and a predominant focus on anorexia nervosa. Further, existing data regarding predictors of outcome have yielded mixed findings. In the current study, we evaluated treatment outcomes and predictors of outcome among a large sample of adolescents with eating disorders presenting to inpatient, residential, partial hospitalization programs, and intensive outpatient programs across the United States. Methods Adolescents (N = 1,971) completed self-report measures of eating disorder symptoms, depression, and anxiety at treatment admission, stepdown, and discharge. Using linear mixed effect models, we evaluated changes in symptoms over treatment separately among youth admitted to inpatient/residential treatment and those admitted to partial hospitalization/intensive outpatient programs, and used established metrics to gauge frequency of reliable (i.e., statistically reliable) and clinically significant change. Results Results suggested decreases in eating disorder symptoms, depression, and anxiety from intake to discharge. Around 50% of the sample reported reliable decreases in eating disorder symptoms at stepdown and discharge, with 30% of the sample reporting reliable reductions in depression and anxiety. Psychiatric comorbidity, primary diagnosis, age, and eating disorder symptoms at admission consistently predicted treatment-related change, although patterns in findings varied across symptoms. Conclusions Data from our sample are consistent with past work suggesting that adolescents enrolled in higher levels of care report clinical benefit; however, these effects are heterogenous, and a significant portion of individuals may not report reliable change in symptoms. Ultimately, ongoing work is required to better understand how and for whom higher levels of care may achieve their benefit and to identify the optimal approach for improving outcomes for adolescents with eating disorders.
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spelling doaj-art-5001bc750d7241bfb1a2764670c2aae52025-02-02T12:08:58ZengBMCChild and Adolescent Psychiatry and Mental Health1753-20002024-10-0118111710.1186/s13034-024-00819-8Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disordersErin E. Reilly0Sasha Gorrell1Alan Duffy2Dan V. Blalock3Philip Mehler4Harry Brandt5Susan McClanahan6Kianna Zucker7Naomi Lynch8Simar Singh9Catherine R. Drury10Daniel Le Grange11Renee D. Rienecke12Department of Psychiatry and Behavioral Sciences, University of California, San FranciscoDepartment of Psychiatry and Behavioral Sciences, University of California, San FranciscoEating Recovery Center/Pathlight Mood & Anxiety CenterCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical CenterEating Recovery Center/Pathlight Mood & Anxiety CenterEating Recovery Center/Pathlight Mood & Anxiety CenterEating Recovery Center/Pathlight Mood & Anxiety CenterDepartment of Psychiatry and Behavioral Sciences, University of California, San FranciscoDepartment of Psychiatry and Behavioral Sciences, University of California, San FranciscoDepartment of Psychiatry and Behavioral Sciences, University of California, San FranciscoDepartment of Psychiatry and Behavioral Sciences, University of California, San FranciscoDepartment of Psychiatry and Behavioral Sciences, University of California, San FranciscoEating Recovery Center/Pathlight Mood & Anxiety CenterAbstract Background Despite widespread use of higher levels of care in treating eating disorders in adolescents, research supporting the use of these treatments remains limited by small sample sizes and a predominant focus on anorexia nervosa. Further, existing data regarding predictors of outcome have yielded mixed findings. In the current study, we evaluated treatment outcomes and predictors of outcome among a large sample of adolescents with eating disorders presenting to inpatient, residential, partial hospitalization programs, and intensive outpatient programs across the United States. Methods Adolescents (N = 1,971) completed self-report measures of eating disorder symptoms, depression, and anxiety at treatment admission, stepdown, and discharge. Using linear mixed effect models, we evaluated changes in symptoms over treatment separately among youth admitted to inpatient/residential treatment and those admitted to partial hospitalization/intensive outpatient programs, and used established metrics to gauge frequency of reliable (i.e., statistically reliable) and clinically significant change. Results Results suggested decreases in eating disorder symptoms, depression, and anxiety from intake to discharge. Around 50% of the sample reported reliable decreases in eating disorder symptoms at stepdown and discharge, with 30% of the sample reporting reliable reductions in depression and anxiety. Psychiatric comorbidity, primary diagnosis, age, and eating disorder symptoms at admission consistently predicted treatment-related change, although patterns in findings varied across symptoms. Conclusions Data from our sample are consistent with past work suggesting that adolescents enrolled in higher levels of care report clinical benefit; however, these effects are heterogenous, and a significant portion of individuals may not report reliable change in symptoms. Ultimately, ongoing work is required to better understand how and for whom higher levels of care may achieve their benefit and to identify the optimal approach for improving outcomes for adolescents with eating disorders.https://doi.org/10.1186/s13034-024-00819-8AdolescentsEating disordersTreatmentOutcomesHigher levels of care
spellingShingle Erin E. Reilly
Sasha Gorrell
Alan Duffy
Dan V. Blalock
Philip Mehler
Harry Brandt
Susan McClanahan
Kianna Zucker
Naomi Lynch
Simar Singh
Catherine R. Drury
Daniel Le Grange
Renee D. Rienecke
Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
Child and Adolescent Psychiatry and Mental Health
Adolescents
Eating disorders
Treatment
Outcomes
Higher levels of care
title Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
title_full Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
title_fullStr Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
title_full_unstemmed Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
title_short Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
title_sort predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders
topic Adolescents
Eating disorders
Treatment
Outcomes
Higher levels of care
url https://doi.org/10.1186/s13034-024-00819-8
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