The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition characterized by hyperglycemia that persists. Diabetes mellitus can cause damage to multiple organ systems, leading to the development of severe and life-threatening health issues, due to decreased insulin secretion, resistance to per...
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middle technical university
2022-09-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/540 |
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| author | Karar Kazem Mohammed Ahmed Ghazi Sabbar Haider Hafid Hmeash |
| author_facet | Karar Kazem Mohammed Ahmed Ghazi Sabbar Haider Hafid Hmeash |
| author_sort | Karar Kazem Mohammed |
| collection | DOAJ |
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Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition characterized by hyperglycemia that persists. Diabetes mellitus can cause damage to multiple organ systems, leading to the development of severe and life-threatening health issues, due to decreased insulin secretion, resistance to peripheral insulin effects, or both.
Objective: the comparison and correlation of serum levels of insulin and Na+/ K+ ATPase in T2DM and Non-Diabetic patients.
Material and methods: A case-control study was carried out in the max cure diabetes center and Al-Zahra Teaching Hospital in the city of AL-Kut, Iraq. Including 114 patients divided into 54 patients of T2DM in addition to 60 individuals as control (male and female), ages ranging from (20-70 years) from November 2021 –to March 2022. It was the measurement of serum Na+/K+ATPase and insulin level.
Results: In the comparison of insulin levels in Type 2 Diabetes Mellitus (T2DM) and healthy control group, serum insulin was found to be significantly decreased (p value<0.005) and Na+/K+ ATPase significantly decrease with a (p value<0.001) in diabetics as compared to control group. The correlation was positive and significant between the serum Na+/K+ ATPase and insulin.
Conclusions: serum insulin and Na+/K+ ATPase showed a significant decrease in diabetics as compared to the control group. Whereas a significant positive correlation is obtained between the parameters.
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| format | Article |
| id | doaj-art-4ff8723e68b247f9bff23d5b98caad07 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-4ff8723e68b247f9bff23d5b98caad072025-01-19T11:07:11Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-09-014310.51173/jt.v4i3.540The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus IndividualsKarar Kazem Mohammed0Ahmed Ghazi Sabbar1Haider Hafid Hmeash2College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition characterized by hyperglycemia that persists. Diabetes mellitus can cause damage to multiple organ systems, leading to the development of severe and life-threatening health issues, due to decreased insulin secretion, resistance to peripheral insulin effects, or both. Objective: the comparison and correlation of serum levels of insulin and Na+/ K+ ATPase in T2DM and Non-Diabetic patients. Material and methods: A case-control study was carried out in the max cure diabetes center and Al-Zahra Teaching Hospital in the city of AL-Kut, Iraq. Including 114 patients divided into 54 patients of T2DM in addition to 60 individuals as control (male and female), ages ranging from (20-70 years) from November 2021 –to March 2022. It was the measurement of serum Na+/K+ATPase and insulin level. Results: In the comparison of insulin levels in Type 2 Diabetes Mellitus (T2DM) and healthy control group, serum insulin was found to be significantly decreased (p value<0.005) and Na+/K+ ATPase significantly decrease with a (p value<0.001) in diabetics as compared to control group. The correlation was positive and significant between the serum Na+/K+ ATPase and insulin. Conclusions: serum insulin and Na+/K+ ATPase showed a significant decrease in diabetics as compared to the control group. Whereas a significant positive correlation is obtained between the parameters. https://journal.mtu.edu.iq/index.php/MTU/article/view/540Type 2 Diabetes Mellitus (T2DM)InsulinNa /K ATPaseHyperglycemiaBeta-cell |
| spellingShingle | Karar Kazem Mohammed Ahmed Ghazi Sabbar Haider Hafid Hmeash The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals Journal of Techniques Type 2 Diabetes Mellitus (T2DM) Insulin Na /K ATPase Hyperglycemia Beta-cell |
| title | The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals |
| title_full | The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals |
| title_fullStr | The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals |
| title_full_unstemmed | The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals |
| title_short | The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals |
| title_sort | comparison and correlation of serum levels of insulin and na k atpase in type 2 diabetes mellitus t2dm and non diabetes mellitus individuals |
| topic | Type 2 Diabetes Mellitus (T2DM) Insulin Na /K ATPase Hyperglycemia Beta-cell |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/540 |
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