The Comparison and Correlation of Serum Levels of Insulin and Na+/ K+ Atpase In Type 2 Diabetes Mellitus (T2DM) And Non-Diabetes Mellitus Individuals
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition characterized by hyperglycemia that persists. Diabetes mellitus can cause damage to multiple organ systems, leading to the development of severe and life-threatening health issues, due to decreased insulin secretion, resistance to per...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
middle technical university
2022-09-01
|
| Series: | Journal of Techniques |
| Subjects: | |
| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/540 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic condition characterized by hyperglycemia that persists. Diabetes mellitus can cause damage to multiple organ systems, leading to the development of severe and life-threatening health issues, due to decreased insulin secretion, resistance to peripheral insulin effects, or both.
Objective: the comparison and correlation of serum levels of insulin and Na+/ K+ ATPase in T2DM and Non-Diabetic patients.
Material and methods: A case-control study was carried out in the max cure diabetes center and Al-Zahra Teaching Hospital in the city of AL-Kut, Iraq. Including 114 patients divided into 54 patients of T2DM in addition to 60 individuals as control (male and female), ages ranging from (20-70 years) from November 2021 –to March 2022. It was the measurement of serum Na+/K+ATPase and insulin level.
Results: In the comparison of insulin levels in Type 2 Diabetes Mellitus (T2DM) and healthy control group, serum insulin was found to be significantly decreased (p value<0.005) and Na+/K+ ATPase significantly decrease with a (p value<0.001) in diabetics as compared to control group. The correlation was positive and significant between the serum Na+/K+ ATPase and insulin.
Conclusions: serum insulin and Na+/K+ ATPase showed a significant decrease in diabetics as compared to the control group. Whereas a significant positive correlation is obtained between the parameters.
|
|---|---|
| ISSN: | 1818-653X 2708-8383 |