Genomic characterization of invasive Neisseria meningitidis in Spain (2011/12–2022/23): expansion of clonal complex 213 and the potential threat to 4CMenB vaccine strain coverage

Genomic characterization of invasive Neisseria meningitidis in Spain (2011/12–2022/23): expansion of clonal complex 213 and the potential threat to 4CMenB vaccine strain coverage

Invasive meningococcal disease (IMD) is associated with significant global morbidity and mortality and is addressed by conjugated polysaccharide and subcapsular vaccines. In Spain, data on 4CMenB vaccine strain coverage and antimicrobial susceptibility are limited. This study aimed to describe the g...

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Main Authors: Josep Roca-Grande, Alba Mir-Cros, Carmen Muñoz-Almagro, Mayli Lung, Alba Bellés-Bellés, Jordi Càmara, Emilia Cercenado, M. Ángeles Galán-Ladero, Andrea Martín-Nalda, Albert Moreno-Mingorance, Daniel Navarro de la Cruz, M. Ángeles Orellana, Begoña Palop, Amaresh Pérez-Argüello, Guillem Puigsech-Boixeda, M. Dolores Quesada, Alba Rivera, Ana Rodriguez-Fernandez, Enrique Ruiz de Gopegui, Carolina Sarvisé, Aleix Soler-Garcia, Belén Viñado, Nieves Larrosa, Juan José González-López
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Neisseria meningitidis
whole genome sequencing
genomic epidemiology
cc213
gMATS
4CMenB vaccine strain coverage
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2482696
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