Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats
In order to evaluate the effects of extract by SCE (supercritical carbon dioxide extraction) from cole pollen on lipid metabolism in hyperlipidemic rats, the experimental hyperlipidemic rats were established by providing with high fat diets, and randomized into six groups. After four weeks of perfus...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/982498 |
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| author | Yue Geng Wen-li Tu Jing-jing Zhang Liang Zhang Jian Zhang |
| author_facet | Yue Geng Wen-li Tu Jing-jing Zhang Liang Zhang Jian Zhang |
| author_sort | Yue Geng |
| collection | DOAJ |
| description | In order to evaluate the effects of extract by SCE (supercritical carbon dioxide extraction) from cole pollen on lipid metabolism in hyperlipidemic rats, the experimental hyperlipidemic rats were established by providing with high fat diets, and randomized into six groups. After four weeks of perfusion diets into stomach, the rats were executed, and lipid levels of serum and hepatic tissue were detected. The serum levels of TC and TG were significantly lower in the pollen extract groups and MC group than in HFC group. Hepatic TC levels were decreased in rats fed pollen extract and lovastatin compared with HFC group. A higher concentration of HDL-C and apoAI in hepatic tissue was measured after intake of the pollen extract compared to the HFC group (P<0.05). LCAT activity in serum of pollen extract groups was significantly higher than that in HFC group, and also HMG-CoA reductase showed decreasing tendency in pollen extract groups. The contents of DHA in pollen extract groups were found higher than those in HFC group. Cole pollen extract enriched in alpha-linolenic acid is likely to be a novel source of ALA which is probably responsible for favorable lipid changes through promoting transportation, excretion, and metabolism of cholesterol in hepatic tissue and serum. |
| format | Article |
| id | doaj-art-4f725a0a3433457bb8b124097142362d |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-4f725a0a3433457bb8b124097142362d2025-02-03T01:12:57ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/982498982498Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic RatsYue Geng0Wen-li Tu1Jing-jing Zhang2Liang Zhang3Jian Zhang4Provincial Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University, Jinan 250014, ChinaProvincial Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University, Jinan 250014, ChinaProvincial Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University, Jinan 250014, ChinaProvincial Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University, Jinan 250014, ChinaProvincial Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University, Jinan 250014, ChinaIn order to evaluate the effects of extract by SCE (supercritical carbon dioxide extraction) from cole pollen on lipid metabolism in hyperlipidemic rats, the experimental hyperlipidemic rats were established by providing with high fat diets, and randomized into six groups. After four weeks of perfusion diets into stomach, the rats were executed, and lipid levels of serum and hepatic tissue were detected. The serum levels of TC and TG were significantly lower in the pollen extract groups and MC group than in HFC group. Hepatic TC levels were decreased in rats fed pollen extract and lovastatin compared with HFC group. A higher concentration of HDL-C and apoAI in hepatic tissue was measured after intake of the pollen extract compared to the HFC group (P<0.05). LCAT activity in serum of pollen extract groups was significantly higher than that in HFC group, and also HMG-CoA reductase showed decreasing tendency in pollen extract groups. The contents of DHA in pollen extract groups were found higher than those in HFC group. Cole pollen extract enriched in alpha-linolenic acid is likely to be a novel source of ALA which is probably responsible for favorable lipid changes through promoting transportation, excretion, and metabolism of cholesterol in hepatic tissue and serum.http://dx.doi.org/10.1155/2014/982498 |
| spellingShingle | Yue Geng Wen-li Tu Jing-jing Zhang Liang Zhang Jian Zhang Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats The Scientific World Journal |
| title | Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats |
| title_full | Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats |
| title_fullStr | Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats |
| title_full_unstemmed | Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats |
| title_short | Effects of Extract from Cole Pollen on Lipid Metabolism in Experimental Hyperlipidemic Rats |
| title_sort | effects of extract from cole pollen on lipid metabolism in experimental hyperlipidemic rats |
| url | http://dx.doi.org/10.1155/2014/982498 |
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