Visual detection of cyanide using ninhydrin coated paper
Humans are often exposed to cyanide through drinking water or by eating plants that contain cyanogenic glucosides (e.g. cassava – a staple source of carbohydrates). Many methods exist to detect cyanide, but few are safe, cheap and easy to perform for an untrained user. In this work, we demonstrate t...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Heliyon |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025006632 |
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| author | Syafril Hidayat Rachadaporn Benchawattananon Lapatrada Taemaitree |
| author_facet | Syafril Hidayat Rachadaporn Benchawattananon Lapatrada Taemaitree |
| author_sort | Syafril Hidayat |
| collection | DOAJ |
| description | Humans are often exposed to cyanide through drinking water or by eating plants that contain cyanogenic glucosides (e.g. cassava – a staple source of carbohydrates). Many methods exist to detect cyanide, but few are safe, cheap and easy to perform for an untrained user. In this work, we demonstrate that Whatman paper can be coated with ninhydrin and that the addition of basic solutions of cyanide gives an immediate pale yellow to red colour change. The ninhydrin paper can be used to visually, semi-quantitatively detect cyanide at concentrations up to ∼5 μg/mL (in 30 μL; 0.15 μg), and can be stored for several months. Most importantly, we show the paper can be used to monitor the release of cyanide from plants such as cassava leaves as they are processed in cooking suggesting the paper could be used in-the-field. |
| format | Article |
| id | doaj-art-4f5b83f89f0a4b22a952dc89687b86bd |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-4f5b83f89f0a4b22a952dc89687b86bd2025-02-03T04:16:48ZengElsevierHeliyon2405-84402025-02-01113e42283Visual detection of cyanide using ninhydrin coated paperSyafril Hidayat0Rachadaporn Benchawattananon1Lapatrada Taemaitree2Department of Integrated Science, Forensic Science Program, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, ThailandDepartment of Integrated Science, Forensic Science Program, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, ThailandCorresponding author.; Department of Integrated Science, Forensic Science Program, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, ThailandHumans are often exposed to cyanide through drinking water or by eating plants that contain cyanogenic glucosides (e.g. cassava – a staple source of carbohydrates). Many methods exist to detect cyanide, but few are safe, cheap and easy to perform for an untrained user. In this work, we demonstrate that Whatman paper can be coated with ninhydrin and that the addition of basic solutions of cyanide gives an immediate pale yellow to red colour change. The ninhydrin paper can be used to visually, semi-quantitatively detect cyanide at concentrations up to ∼5 μg/mL (in 30 μL; 0.15 μg), and can be stored for several months. Most importantly, we show the paper can be used to monitor the release of cyanide from plants such as cassava leaves as they are processed in cooking suggesting the paper could be used in-the-field.http://www.sciencedirect.com/science/article/pii/S2405844025006632 |
| spellingShingle | Syafril Hidayat Rachadaporn Benchawattananon Lapatrada Taemaitree Visual detection of cyanide using ninhydrin coated paper Heliyon |
| title | Visual detection of cyanide using ninhydrin coated paper |
| title_full | Visual detection of cyanide using ninhydrin coated paper |
| title_fullStr | Visual detection of cyanide using ninhydrin coated paper |
| title_full_unstemmed | Visual detection of cyanide using ninhydrin coated paper |
| title_short | Visual detection of cyanide using ninhydrin coated paper |
| title_sort | visual detection of cyanide using ninhydrin coated paper |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025006632 |
| work_keys_str_mv | AT syafrilhidayat visualdetectionofcyanideusingninhydrincoatedpaper AT rachadapornbenchawattananon visualdetectionofcyanideusingninhydrincoatedpaper AT lapatradataemaitree visualdetectionofcyanideusingninhydrincoatedpaper |