Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients

In a recent study we found no difference in the concentrations of luminal lactate in the rectum between nonsurvivors and survivors in early septic shock (<24 h). This study was initiated to investigate if there are any changes in the concentrations of luminal lactate in the rectum during the firs...

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Main Authors: Michael Ibsen, Jørgen Wiis, Tina Waldau, Anders Perner
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/504096
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author Michael Ibsen
Jørgen Wiis
Tina Waldau
Anders Perner
author_facet Michael Ibsen
Jørgen Wiis
Tina Waldau
Anders Perner
author_sort Michael Ibsen
collection DOAJ
description In a recent study we found no difference in the concentrations of luminal lactate in the rectum between nonsurvivors and survivors in early septic shock (<24 h). This study was initiated to investigate if there are any changes in the concentrations of luminal lactate in the rectum during the first 3 days of septic shock and possible differences between nonsurvivors and survivors. Methods. We studied 22 patients with septic shock in this observational study. Six to 24 h after the onset of septic shock the concentration of lactate in the rectal lumen was estimated by 4 h equilibrium dialysis (day 1). The rectal dialysis was repeated on day 2 and day 3. Results. The concentration of lactate in the rectal lumen did not change over the 3 days in neither nonsurvivors nor survivors. Rectal luminal and arterial lactate concentrations were not different. Conclusion. There was no change in the concentration of lactate in the rectal lumen over time in patients with septic shock. Also, there was no difference between nonsurvivors and survivors.
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spelling doaj-art-4f4ec4386ac144eb9a234c78673275562025-02-03T06:11:02ZengWileyCritical Care Research and Practice2090-13052090-13132012-01-01201210.1155/2012/504096504096Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock PatientsMichael Ibsen0Jørgen Wiis1Tina Waldau2Anders Perner3Intensive CareUnit 4131, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, DenmarkIntensive CareUnit 4131, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, DenmarkDepartment of Anaesthesia and Intensive Care, Herlev Hospital, University of Copenhagen, 2730 Herlev, DenmarkIntensive CareUnit 4131, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, DenmarkIn a recent study we found no difference in the concentrations of luminal lactate in the rectum between nonsurvivors and survivors in early septic shock (<24 h). This study was initiated to investigate if there are any changes in the concentrations of luminal lactate in the rectum during the first 3 days of septic shock and possible differences between nonsurvivors and survivors. Methods. We studied 22 patients with septic shock in this observational study. Six to 24 h after the onset of septic shock the concentration of lactate in the rectal lumen was estimated by 4 h equilibrium dialysis (day 1). The rectal dialysis was repeated on day 2 and day 3. Results. The concentration of lactate in the rectal lumen did not change over the 3 days in neither nonsurvivors nor survivors. Rectal luminal and arterial lactate concentrations were not different. Conclusion. There was no change in the concentration of lactate in the rectal lumen over time in patients with septic shock. Also, there was no difference between nonsurvivors and survivors.http://dx.doi.org/10.1155/2012/504096
spellingShingle Michael Ibsen
Jørgen Wiis
Tina Waldau
Anders Perner
Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients
Critical Care Research and Practice
title Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients
title_full Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients
title_fullStr Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients
title_full_unstemmed Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients
title_short Consecutive Daily Measurements of Luminal Concentrations of Lactate in the Rectum in Septic Shock Patients
title_sort consecutive daily measurements of luminal concentrations of lactate in the rectum in septic shock patients
url http://dx.doi.org/10.1155/2012/504096
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