Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking
Purpose. To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). Methods. Functional analysis comprised paediatric patients (≤18 years) included 152 eyes (2...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2011/608041 |
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| author | Aldo Caporossi Cosimo Mazzotta Stefano Baiocchi Tomaso Caporossi Rosario Denaro |
| author_facet | Aldo Caporossi Cosimo Mazzotta Stefano Baiocchi Tomaso Caporossi Rosario Denaro |
| author_sort | Aldo Caporossi |
| collection | DOAJ |
| description | Purpose. To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). Methods. Functional analysis comprised paediatric patients (≤18 years) included 152 eyes (29.5%); intermediate group (19–26 years) 286 eyes (55.4%), and adults (≥27 years) 78 eyes (15.1%). CXL was performed according to the Siena protocol by using the Vega CBM (Caporossi-Baiocchi-Mazzotta) X linker (CSO, Florence, Italy) at Siena University by the same authors. Pre- and post-op examinations included UCVA, BSCVA, corneal topography, and surface aberrometry (CSO Eye Top, Florence, Italy), at 48 months followup. Results. At 48 months followup paediatrics, intermediate, and adult patients showed a mean gain in UCVA of +0.2, +0.14 and +0.12 Snellen lines. BSCVA gained by a mean of +0.21, +0.2, and +0.1 Snellen lines. Kmax was reduced by a mean value of −0.9 D, −0.6 D, and −0.5 D, respectively. Coma values improved by a mean of −0.45 μm, −0.91 μm, and −0.19 μm, respectively. Treatment ensured a long-term keratoconus stabilization in over 90% of treated patients. Conclusion. According to our long-term comparative results, epithelium-off Riboflavin UV A cross-linking should be the first choice therapy of progressive KC, particularly in paediatric age and patients under 26 years. |
| format | Article |
| id | doaj-art-4f343e66f9f34c26a143adb8f6a5305e |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-4f343e66f9f34c26a143adb8f6a5305e2025-02-03T05:51:53ZengWileyJournal of Ophthalmology2090-004X2090-00582011-01-01201110.1155/2011/608041608041Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-LinkingAldo Caporossi0Cosimo Mazzotta1Stefano Baiocchi2Tomaso Caporossi3Rosario Denaro4Department of Ophthalmology, University of Siena, 53100 Siena, ItalyDepartment of Ophthalmology, University of Siena, 53100 Siena, ItalyDepartment of Ophthalmology, University of Siena, 53100 Siena, ItalyDepartment of Ophthalmology, Catholic University, Rome, ItalyDepartment of Ophthalmology, University of Siena, 53100 Siena, ItalyPurpose. To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). Methods. Functional analysis comprised paediatric patients (≤18 years) included 152 eyes (29.5%); intermediate group (19–26 years) 286 eyes (55.4%), and adults (≥27 years) 78 eyes (15.1%). CXL was performed according to the Siena protocol by using the Vega CBM (Caporossi-Baiocchi-Mazzotta) X linker (CSO, Florence, Italy) at Siena University by the same authors. Pre- and post-op examinations included UCVA, BSCVA, corneal topography, and surface aberrometry (CSO Eye Top, Florence, Italy), at 48 months followup. Results. At 48 months followup paediatrics, intermediate, and adult patients showed a mean gain in UCVA of +0.2, +0.14 and +0.12 Snellen lines. BSCVA gained by a mean of +0.21, +0.2, and +0.1 Snellen lines. Kmax was reduced by a mean value of −0.9 D, −0.6 D, and −0.5 D, respectively. Coma values improved by a mean of −0.45 μm, −0.91 μm, and −0.19 μm, respectively. Treatment ensured a long-term keratoconus stabilization in over 90% of treated patients. Conclusion. According to our long-term comparative results, epithelium-off Riboflavin UV A cross-linking should be the first choice therapy of progressive KC, particularly in paediatric age and patients under 26 years.http://dx.doi.org/10.1155/2011/608041 |
| spellingShingle | Aldo Caporossi Cosimo Mazzotta Stefano Baiocchi Tomaso Caporossi Rosario Denaro Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking Journal of Ophthalmology |
| title | Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking |
| title_full | Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking |
| title_fullStr | Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking |
| title_full_unstemmed | Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking |
| title_short | Age-Related Long-Term Functional Results after Riboflavin UV A Corneal Cross-Linking |
| title_sort | age related long term functional results after riboflavin uv a corneal cross linking |
| url | http://dx.doi.org/10.1155/2011/608041 |
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