Anaphylactic shock induced by intravenous ketorolac: A case report
Ketorolac trometamol injection is the first injectable nonsteroidal anti-inflammatory drug (NSAID) approved for the short-term management of moderate to severe pain. As a non-opioid alternative, it represents a critical development for acute pain relief, particularly in postoperative and injury-rela...
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| Language: | English |
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Elsevier
2025-02-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025006164 |
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| author | Huijuan Lu Kaili Lai Shuzhu Lin Guining Dang |
| author_facet | Huijuan Lu Kaili Lai Shuzhu Lin Guining Dang |
| author_sort | Huijuan Lu |
| collection | DOAJ |
| description | Ketorolac trometamol injection is the first injectable nonsteroidal anti-inflammatory drug (NSAID) approved for the short-term management of moderate to severe pain. As a non-opioid alternative, it represents a critical development for acute pain relief, particularly in postoperative and injury-related scenarios. Like other NSAIDs, ketorolac trometamol is associated with common adverse reactions such as dizziness, headache, drowsiness, nausea, and vomiting, which are generally mild to moderate. However, rare but severe reactions like anaphylactic shock have been reported. This case report highlights a specific instance of anaphylactic shock induced by intravenous ketorolac trometamol, emphasizing the rapid onset of symptoms and the importance of vigilant monitoring during administration to prevent severe outcomes. Additionally, recommendations for post-recovery monitoring and allergological evaluation are provided to enhance clinical management in similar cases. |
| format | Article |
| id | doaj-art-4f1e5ec2a5234436b719b85fd850670e |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-4f1e5ec2a5234436b719b85fd850670e2025-02-03T04:16:48ZengElsevierHeliyon2405-84402025-02-01113e42236Anaphylactic shock induced by intravenous ketorolac: A case reportHuijuan Lu0Kaili Lai1Shuzhu Lin2Guining Dang3Department of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, ChinaDepartment of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, ChinaDepartment of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, ChinaCorresponding author.; Department of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, ChinaKetorolac trometamol injection is the first injectable nonsteroidal anti-inflammatory drug (NSAID) approved for the short-term management of moderate to severe pain. As a non-opioid alternative, it represents a critical development for acute pain relief, particularly in postoperative and injury-related scenarios. Like other NSAIDs, ketorolac trometamol is associated with common adverse reactions such as dizziness, headache, drowsiness, nausea, and vomiting, which are generally mild to moderate. However, rare but severe reactions like anaphylactic shock have been reported. This case report highlights a specific instance of anaphylactic shock induced by intravenous ketorolac trometamol, emphasizing the rapid onset of symptoms and the importance of vigilant monitoring during administration to prevent severe outcomes. Additionally, recommendations for post-recovery monitoring and allergological evaluation are provided to enhance clinical management in similar cases.http://www.sciencedirect.com/science/article/pii/S2405844025006164Ketorolac trometamolAnaphylactic shockAnaphylaxisIntravenous injectionAdverse drug reactionCase report |
| spellingShingle | Huijuan Lu Kaili Lai Shuzhu Lin Guining Dang Anaphylactic shock induced by intravenous ketorolac: A case report Heliyon Ketorolac trometamol Anaphylactic shock Anaphylaxis Intravenous injection Adverse drug reaction Case report |
| title | Anaphylactic shock induced by intravenous ketorolac: A case report |
| title_full | Anaphylactic shock induced by intravenous ketorolac: A case report |
| title_fullStr | Anaphylactic shock induced by intravenous ketorolac: A case report |
| title_full_unstemmed | Anaphylactic shock induced by intravenous ketorolac: A case report |
| title_short | Anaphylactic shock induced by intravenous ketorolac: A case report |
| title_sort | anaphylactic shock induced by intravenous ketorolac a case report |
| topic | Ketorolac trometamol Anaphylactic shock Anaphylaxis Intravenous injection Adverse drug reaction Case report |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025006164 |
| work_keys_str_mv | AT huijuanlu anaphylacticshockinducedbyintravenousketorolacacasereport AT kaililai anaphylacticshockinducedbyintravenousketorolacacasereport AT shuzhulin anaphylacticshockinducedbyintravenousketorolacacasereport AT guiningdang anaphylacticshockinducedbyintravenousketorolacacasereport |