Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study
Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. In this report, we discuss our findings about a scalp psoriasis suffering patient with a Psoriasis Scalp Severity Index (PSSI) score of 28, who was treated with Mesenchymal stem cell conditioned media (MSC-CM). Rema...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/8309103 |
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| author | Rajasekar Seetharaman Anjum Mahmood Prashant Kshatriya Divyang Patel Anand Srivastava |
| author_facet | Rajasekar Seetharaman Anjum Mahmood Prashant Kshatriya Divyang Patel Anand Srivastava |
| author_sort | Rajasekar Seetharaman |
| collection | DOAJ |
| description | Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. In this report, we discuss our findings about a scalp psoriasis suffering patient with a Psoriasis Scalp Severity Index (PSSI) score of 28, who was treated with Mesenchymal stem cell conditioned media (MSC-CM). Remarkably, complete regression was recorded within a treatment period of one month only (PSSI score of 0). A number of bioactive factors like cytokines and growth factors secreted by MSCs in the conditioned medium are very likely to be the principle molecules which play a vital role in skin regeneration. Treatment using MSC-CM appears to be an effective tool for tackling the psoriatic problem and, thus, may offer a new avenue of therapy which could be considered as an alternative approach to overcome the limitations of the cell-based therapy. |
| format | Article |
| id | doaj-art-4f129b8a9e4c4b228790c16b6065e5f3 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-4f129b8a9e4c4b228790c16b6065e5f32025-02-03T01:20:27ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712019-01-01201910.1155/2019/83091038309103Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case StudyRajasekar Seetharaman0Anjum Mahmood1Prashant Kshatriya2Divyang Patel3Anand Srivastava4GIOSTAR Research Inc. Pvt. Ltd., Ahmedabad, Gujrat, IndiaGIOSTAR Research Inc. Pvt. Ltd., Ahmedabad, Gujrat, IndiaGIOSTAR Research Inc. Pvt. Ltd., Ahmedabad, Gujrat, IndiaGIOSTAR Research Inc. Pvt. Ltd., Ahmedabad, Gujrat, IndiaGIOSTAR Research Inc. Pvt. Ltd., Ahmedabad, Gujrat, IndiaPsoriasis, an autoimmune disease, affects a vast number of peoples around the world. In this report, we discuss our findings about a scalp psoriasis suffering patient with a Psoriasis Scalp Severity Index (PSSI) score of 28, who was treated with Mesenchymal stem cell conditioned media (MSC-CM). Remarkably, complete regression was recorded within a treatment period of one month only (PSSI score of 0). A number of bioactive factors like cytokines and growth factors secreted by MSCs in the conditioned medium are very likely to be the principle molecules which play a vital role in skin regeneration. Treatment using MSC-CM appears to be an effective tool for tackling the psoriatic problem and, thus, may offer a new avenue of therapy which could be considered as an alternative approach to overcome the limitations of the cell-based therapy.http://dx.doi.org/10.1155/2019/8309103 |
| spellingShingle | Rajasekar Seetharaman Anjum Mahmood Prashant Kshatriya Divyang Patel Anand Srivastava Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study Case Reports in Dermatological Medicine |
| title | Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study |
| title_full | Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study |
| title_fullStr | Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study |
| title_full_unstemmed | Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study |
| title_short | Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study |
| title_sort | mesenchymal stem cell conditioned media ameliorate psoriasis vulgaris a case study |
| url | http://dx.doi.org/10.1155/2019/8309103 |
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