Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival

Small bowel adenocarcinoma is a rare but well-known complication of Crohn’s disease. The diagnosis of small bowel adenocarcinoma remains difficult since its presentation is highly variable and mimics active or obstructive Crohn’s disease. The diagnosis is often delayed and typically detected only at...

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Main Authors: Jiten P. Kothadia, Deepa H. Nagaraju, Seymour Katz, Howard Bruckner, Steven H. Itzkowitz, Myron Schwartz
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2019/8473829
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author Jiten P. Kothadia
Deepa H. Nagaraju
Seymour Katz
Howard Bruckner
Steven H. Itzkowitz
Myron Schwartz
author_facet Jiten P. Kothadia
Deepa H. Nagaraju
Seymour Katz
Howard Bruckner
Steven H. Itzkowitz
Myron Schwartz
author_sort Jiten P. Kothadia
collection DOAJ
description Small bowel adenocarcinoma is a rare but well-known complication of Crohn’s disease. The diagnosis of small bowel adenocarcinoma remains difficult since its presentation is highly variable and mimics active or obstructive Crohn’s disease. The diagnosis is often delayed and typically detected only at surgery in an advanced stage with a poor prognosis. We report a case of metastatic ileal adenocarcinoma in a patient with Crohn’s disease with prolonged survival. Our case describes serial promising treatment options of these advanced malignancies and raises a possible role for checkpoint immunotherapy.
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institution Kabale University
issn 2090-6706
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language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Oncological Medicine
spelling doaj-art-4f09ba107e5f4908b1f8205327291e3e2025-02-03T06:48:37ZengWileyCase Reports in Oncological Medicine2090-67062090-67142019-01-01201910.1155/2019/84738298473829Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year SurvivalJiten P. Kothadia0Deepa H. Nagaraju1Seymour Katz2Howard Bruckner3Steven H. Itzkowitz4Myron Schwartz5MUH James D. Eason Transplant Institute, University of Tennessee Health Sciences Center, 1265 Union Avenue, 4 Shorb Tower, Memphis, TN 38104, USAUF Health Family Medicine and Pediatrics, 8274 Bayberry Road Jacksonville, FL 32256, USADepartment of Gastroenterology, NYU Langone Medical Center, 1000 Northern Blvd, Great Neck, NY 11021, USABruckner Oncology, 2330 Eastchester Road, Bronx, NY 10469, USADivision of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USAThe Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USASmall bowel adenocarcinoma is a rare but well-known complication of Crohn’s disease. The diagnosis of small bowel adenocarcinoma remains difficult since its presentation is highly variable and mimics active or obstructive Crohn’s disease. The diagnosis is often delayed and typically detected only at surgery in an advanced stage with a poor prognosis. We report a case of metastatic ileal adenocarcinoma in a patient with Crohn’s disease with prolonged survival. Our case describes serial promising treatment options of these advanced malignancies and raises a possible role for checkpoint immunotherapy.http://dx.doi.org/10.1155/2019/8473829
spellingShingle Jiten P. Kothadia
Deepa H. Nagaraju
Seymour Katz
Howard Bruckner
Steven H. Itzkowitz
Myron Schwartz
Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival
Case Reports in Oncological Medicine
title Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival
title_full Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival
title_fullStr Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival
title_full_unstemmed Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival
title_short Ileal Adenocarcinoma with Liver Metastasis in Patient with Crohn’s Disease: A 9-Year Survival
title_sort ileal adenocarcinoma with liver metastasis in patient with crohn s disease a 9 year survival
url http://dx.doi.org/10.1155/2019/8473829
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