Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens

This study investigated the effects of dietary housefly larvae meal (HFLM) and Rayabold (multi-enzyme-probiotic supplement) on the performance, egg quality, and blood biochemistry of 192 Lohmann LSL-Lite laying hens at 56 weeks of age. A 10-week feeding trial was conducted using a 4 × 2 factorial de...

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Main Authors: Abolfazl Salehizadeh, Ph.D, Mehran Torki, Ph.D, Maryam Darbemamieh, Ph.D, Seyed Davood Sharifi, Ph.D
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Applied Food Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772502225005815
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author Abolfazl Salehizadeh, Ph.D
Mehran Torki, Ph.D
Maryam Darbemamieh, Ph.D
Seyed Davood Sharifi, Ph.D
author_facet Abolfazl Salehizadeh, Ph.D
Mehran Torki, Ph.D
Maryam Darbemamieh, Ph.D
Seyed Davood Sharifi, Ph.D
author_sort Abolfazl Salehizadeh, Ph.D
collection DOAJ
description This study investigated the effects of dietary housefly larvae meal (HFLM) and Rayabold (multi-enzyme-probiotic supplement) on the performance, egg quality, and blood biochemistry of 192 Lohmann LSL-Lite laying hens at 56 weeks of age. A 10-week feeding trial was conducted using a 4 × 2 factorial design, with four HFLM inclusion levels (0, 5, 10, and 15 %) and two Rayabold levels (0 and 0.05 %). The inclusion of HFLM, with or without Rayabold, significantly reduced feed intake compared to the control; however, Rayabold partially offset this reduction at the 5 % and 10 % HFLM levels. Although feed intake was reduced, egg production remained unaffected, while egg weight increased notably in hens receiving 15 % HFLM combined with Rayabold. Both 10 % and 15 % inclusion levels of HFLM improved feed conversion ratio, protein efficiency, and energy efficiency, with Rayabold further enhanced protein and energy utilization at the 15 % inclusion level. Eggshell weight, thickness, and yolk height improved significantly in the 15 % HFLM + Rayabold group. Metabolic responses included reduced blood glucose at 5 % and 10 % HFLM, and lower cholesterol at 10 %. Furthermore, triglyceride levels declined with both HFLM and Rayabold supplementation. Aspartate aminotransferase activity decreased in the 10 % and 15 % HFLM groups, while alanine aminotransferase was highest in the 15 % + Rayabold group, suggesting possible hepatic stress. Overall, 10 % inclusion of HFLM, with or without Rayabold, offers a nutritionally effective and metabolically safe strategy to enhance laying hen productivity and physiological health, supporting its potential as a sustainable alternative protein source.
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spelling doaj-art-4f0954746f2e43c3a8bb7cf6f9cd61d72025-08-25T04:14:56ZengElsevierApplied Food Research2772-50222025-12-015210127610.1016/j.afres.2025.101276Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hensAbolfazl Salehizadeh, Ph.D0Mehran Torki, Ph.D1Maryam Darbemamieh, Ph.D2Seyed Davood Sharifi, Ph.D3Animal Science Department, College of Agriculture and Natural Resources, Razi University, Kermanshah, Iran, Postal Code: 6715685423Animal Science Department, College of Agriculture and Natural Resources, Razi University, Kermanshah, Iran, Postal Code: 6715685423; Corresponding author.Department of Plant Pathology, College of Agriculture and Natural Resources, Razi University, Kermanshah, IranDepartment of Animal and Poultry Science, Faculty of Agricultural Technology, College of Agriculture and Natural Resources, University of Tehran, Pakdasht, IranThis study investigated the effects of dietary housefly larvae meal (HFLM) and Rayabold (multi-enzyme-probiotic supplement) on the performance, egg quality, and blood biochemistry of 192 Lohmann LSL-Lite laying hens at 56 weeks of age. A 10-week feeding trial was conducted using a 4 × 2 factorial design, with four HFLM inclusion levels (0, 5, 10, and 15 %) and two Rayabold levels (0 and 0.05 %). The inclusion of HFLM, with or without Rayabold, significantly reduced feed intake compared to the control; however, Rayabold partially offset this reduction at the 5 % and 10 % HFLM levels. Although feed intake was reduced, egg production remained unaffected, while egg weight increased notably in hens receiving 15 % HFLM combined with Rayabold. Both 10 % and 15 % inclusion levels of HFLM improved feed conversion ratio, protein efficiency, and energy efficiency, with Rayabold further enhanced protein and energy utilization at the 15 % inclusion level. Eggshell weight, thickness, and yolk height improved significantly in the 15 % HFLM + Rayabold group. Metabolic responses included reduced blood glucose at 5 % and 10 % HFLM, and lower cholesterol at 10 %. Furthermore, triglyceride levels declined with both HFLM and Rayabold supplementation. Aspartate aminotransferase activity decreased in the 10 % and 15 % HFLM groups, while alanine aminotransferase was highest in the 15 % + Rayabold group, suggesting possible hepatic stress. Overall, 10 % inclusion of HFLM, with or without Rayabold, offers a nutritionally effective and metabolically safe strategy to enhance laying hen productivity and physiological health, supporting its potential as a sustainable alternative protein source.http://www.sciencedirect.com/science/article/pii/S2772502225005815Egg qualityEnzymeHousefly larvaeLaying henPerformanceProbiotic
spellingShingle Abolfazl Salehizadeh, Ph.D
Mehran Torki, Ph.D
Maryam Darbemamieh, Ph.D
Seyed Davood Sharifi, Ph.D
Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens
Applied Food Research
Egg quality
Enzyme
Housefly larvae
Laying hen
Performance
Probiotic
title Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens
title_full Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens
title_fullStr Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens
title_full_unstemmed Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens
title_short Effects of housefly larvae meal and multi-enzyme-probiotic supplementation on performance, egg quality, and blood biochemistry in laying hens
title_sort effects of housefly larvae meal and multi enzyme probiotic supplementation on performance egg quality and blood biochemistry in laying hens
topic Egg quality
Enzyme
Housefly larvae
Laying hen
Performance
Probiotic
url http://www.sciencedirect.com/science/article/pii/S2772502225005815
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