Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence
The investigation enrolled 60 infertile patients diagnosed with genital tuberculosis who had completed a basic cycle of etiotropic specific antituberculosis treatment. 53.3% of the women developed adverse reactions (ARs) to anti-TB drugs. In the majority (78.1%) of the patients, chemotherapy for gen...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2015-01-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/332 |
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| _version_ | 1850188508803629056 |
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| author | A. V. Mordyk T. V. Klinyshkova A. A. Yakovleva M. A. Plekhanova |
| author_facet | A. V. Mordyk T. V. Klinyshkova A. A. Yakovleva M. A. Plekhanova |
| author_sort | A. V. Mordyk |
| collection | DOAJ |
| description | The investigation enrolled 60 infertile patients diagnosed with genital tuberculosis who had completed a basic cycle of etiotropic specific antituberculosis treatment. 53.3% of the women developed adverse reactions (ARs) to anti-TB drugs. In the majority (78.1%) of the patients, chemotherapy for genital tuberculosis was complicated by one type of ARs. In the patients with genital tuberculosis and infertility, the most common AR to anti-TB agents was drug-induced hepatitis that was noted in 62.5% of the women. Digestive comorbidity and high adherence to antituberculosis therapy favored the development of ARs in most patients. ARs to anti-TB drugs did not affect the efficiency of treatment for genital tuberculosis in infertile women; however, they contributed to longer treatment in hospital. |
| format | Article |
| id | doaj-art-4f003cd940b64cf28e093a7fcfd3754e |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2015-01-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-4f003cd940b64cf28e093a7fcfd3754e2025-08-20T02:15:52ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062015-01-0101525510.21292/2075-1230-2015-0-1-52-55332Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherenceA. V. Mordyk0T. V. Klinyshkova1A. A. Yakovleva2M. A. Plekhanova3Омская государственная медицинская академия; Клинический противотуберкулезный диспансер № 4, г. ОмскОмская государственная медицинская академия; Клинический противотуберкулезный диспансер № 4, г. ОмскОмская государственная медицинская академия; Клинический противотуберкулезный диспансер № 4Омская государственная медицинская академия; Клинический противотуберкулезный диспансер № 4, г. ОмскThe investigation enrolled 60 infertile patients diagnosed with genital tuberculosis who had completed a basic cycle of etiotropic specific antituberculosis treatment. 53.3% of the women developed adverse reactions (ARs) to anti-TB drugs. In the majority (78.1%) of the patients, chemotherapy for genital tuberculosis was complicated by one type of ARs. In the patients with genital tuberculosis and infertility, the most common AR to anti-TB agents was drug-induced hepatitis that was noted in 62.5% of the women. Digestive comorbidity and high adherence to antituberculosis therapy favored the development of ARs in most patients. ARs to anti-TB drugs did not affect the efficiency of treatment for genital tuberculosis in infertile women; however, they contributed to longer treatment in hospital.https://www.tibl-journal.com/jour/article/view/332genital tuberculosischemotherapyinfertilitytreatment |
| spellingShingle | A. V. Mordyk T. V. Klinyshkova A. A. Yakovleva M. A. Plekhanova Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence Туберкулез и болезни лёгких genital tuberculosis chemotherapy infertility treatment |
| title | Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence |
| title_full | Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence |
| title_fullStr | Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence |
| title_full_unstemmed | Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence |
| title_short | Frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence |
| title_sort | frequency of adverse reactions during chemotherapy for genital tuberculosis in patients with infertility and high treatment adherence |
| topic | genital tuberculosis chemotherapy infertility treatment |
| url | https://www.tibl-journal.com/jour/article/view/332 |
| work_keys_str_mv | AT avmordyk frequencyofadversereactionsduringchemotherapyforgenitaltuberculosisinpatientswithinfertilityandhightreatmentadherence AT tvklinyshkova frequencyofadversereactionsduringchemotherapyforgenitaltuberculosisinpatientswithinfertilityandhightreatmentadherence AT aayakovleva frequencyofadversereactionsduringchemotherapyforgenitaltuberculosisinpatientswithinfertilityandhightreatmentadherence AT maplekhanova frequencyofadversereactionsduringchemotherapyforgenitaltuberculosisinpatientswithinfertilityandhightreatmentadherence |