Gastrointestinal Microbiota and Some Children Diseases: A Review

The bacterial colonization is defined immediately after birth, through direct contact with maternal microbiota and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation...

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Main Authors: Thabata Koester Weber, Isabel Polanco
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/676585
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author Thabata Koester Weber
Isabel Polanco
author_facet Thabata Koester Weber
Isabel Polanco
author_sort Thabata Koester Weber
collection DOAJ
description The bacterial colonization is defined immediately after birth, through direct contact with maternal microbiota and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation of immune system leading to intra- or extra-intestinal diseases. A balance between pathogenic and beneficial microbiota throughout childhood and adolescence is important to gastrointestinal health, including protection against pathogens, inhibition of pathogens, nutrient processing (synthesis of vitamin K), stimulation of angiogenesis, and regulation of host fat storage. Probiotics can promote an intentional modulation of intestinal microbiota favoring the health of the host. This paper is a review about modulation of intestinal microbiota on prevention and adjuvant treatment of pediatric gastrointestinal diseases.
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spelling doaj-art-4ef111d1783248178052e960631e4cf82025-02-03T05:59:39ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/676585676585Gastrointestinal Microbiota and Some Children Diseases: A ReviewThabata Koester Weber0Isabel Polanco1Department of Paediatric Gastroenterology and Nutrition, Children's University Hospital “La Paz”, Autonomous University of Madrid, Paseo de la Castellana 261, 28046 Madrid, SpainDepartment of Paediatric Gastroenterology and Nutrition, Children's University Hospital “La Paz”, Autonomous University of Madrid, Paseo de la Castellana 261, 28046 Madrid, SpainThe bacterial colonization is defined immediately after birth, through direct contact with maternal microbiota and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation of immune system leading to intra- or extra-intestinal diseases. A balance between pathogenic and beneficial microbiota throughout childhood and adolescence is important to gastrointestinal health, including protection against pathogens, inhibition of pathogens, nutrient processing (synthesis of vitamin K), stimulation of angiogenesis, and regulation of host fat storage. Probiotics can promote an intentional modulation of intestinal microbiota favoring the health of the host. This paper is a review about modulation of intestinal microbiota on prevention and adjuvant treatment of pediatric gastrointestinal diseases.http://dx.doi.org/10.1155/2012/676585
spellingShingle Thabata Koester Weber
Isabel Polanco
Gastrointestinal Microbiota and Some Children Diseases: A Review
Gastroenterology Research and Practice
title Gastrointestinal Microbiota and Some Children Diseases: A Review
title_full Gastrointestinal Microbiota and Some Children Diseases: A Review
title_fullStr Gastrointestinal Microbiota and Some Children Diseases: A Review
title_full_unstemmed Gastrointestinal Microbiota and Some Children Diseases: A Review
title_short Gastrointestinal Microbiota and Some Children Diseases: A Review
title_sort gastrointestinal microbiota and some children diseases a review
url http://dx.doi.org/10.1155/2012/676585
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