Regulation of PPARγ Coactivator-1α Function and Expression in Muscle: Effect of Exercise
PPARγ coactivator-1α (PGC-1α) is considered to be a major regulator of mitochondrial biogenesis. Though first discovered in brown adipose tissue, this coactivator has emerged as a coordinator of mitochondrial biogenesis in skeletal muscle via enhanced transcription of many nuclear genes encoding mit...
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| Main Authors: | Giulia Uguccioni, Donna D'souza, David A. Hood |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2010/937123 |
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