Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance

Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance

A radioresistant cell line was established by fractionated ionizing radiation (IR) and assessed by a clonogenic assay, flow cytometry, and Western blot analysis, as well as zymography and a wound healing assay. Microarray was performed to profile global expression and to search for differentially ex...

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Bibliographic Details
Main Authors: Chang-Nim Im, Byeong Mo Kim, Eun-Yi Moon, Da-Won Hong, Joung Whan Park, Sung Hee Hong
Format: Article
Language:English
Published: BioMed Central 2013-12-01
Series:Genomics & Informatics
Subjects:
apoptosis
lung neoplasms
matrix metalloproteinases
radioresistance
syntrophin beta 2
Online Access:http://genominfo.org/upload/pdf/gni-11-245.pdf
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