Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site

Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and imm...

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Main Authors: Daniele Rossini, Salvatore Caponnetto, Vittoria Lapadula, Lucilla De Filippis, Gabriella Del Bene, Alessandra Emiliani, Flavia Longo
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2013/131695
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author Daniele Rossini
Salvatore Caponnetto
Vittoria Lapadula
Lucilla De Filippis
Gabriella Del Bene
Alessandra Emiliani
Flavia Longo
author_facet Daniele Rossini
Salvatore Caponnetto
Vittoria Lapadula
Lucilla De Filippis
Gabriella Del Bene
Alessandra Emiliani
Flavia Longo
author_sort Daniele Rossini
collection DOAJ
description Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.
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institution Kabale University
issn 2090-6706
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language English
publishDate 2013-01-01
publisher Wiley
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series Case Reports in Oncological Medicine
spelling doaj-art-4ec5f60910db4d42bd59e304cd4549ad2025-02-03T01:27:12ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/131695131695Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary SiteDaniele Rossini0Salvatore Caponnetto1Vittoria Lapadula2Lucilla De Filippis3Gabriella Del Bene4Alessandra Emiliani5Flavia Longo6Department of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyMerkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.http://dx.doi.org/10.1155/2013/131695
spellingShingle Daniele Rossini
Salvatore Caponnetto
Vittoria Lapadula
Lucilla De Filippis
Gabriella Del Bene
Alessandra Emiliani
Flavia Longo
Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
Case Reports in Oncological Medicine
title Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_full Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_fullStr Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_full_unstemmed Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_short Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_sort merkel cell carcinoma of the retroperitoneum with no identifiable primary site
url http://dx.doi.org/10.1155/2013/131695
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