Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and imm...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Case Reports in Oncological Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/131695 |
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author | Daniele Rossini Salvatore Caponnetto Vittoria Lapadula Lucilla De Filippis Gabriella Del Bene Alessandra Emiliani Flavia Longo |
author_facet | Daniele Rossini Salvatore Caponnetto Vittoria Lapadula Lucilla De Filippis Gabriella Del Bene Alessandra Emiliani Flavia Longo |
author_sort | Daniele Rossini |
collection | DOAJ |
description | Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy. |
format | Article |
id | doaj-art-4ec5f60910db4d42bd59e304cd4549ad |
institution | Kabale University |
issn | 2090-6706 2090-6714 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Oncological Medicine |
spelling | doaj-art-4ec5f60910db4d42bd59e304cd4549ad2025-02-03T01:27:12ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/131695131695Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary SiteDaniele Rossini0Salvatore Caponnetto1Vittoria Lapadula2Lucilla De Filippis3Gabriella Del Bene4Alessandra Emiliani5Flavia Longo6Department of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Clinical Oncology A, Sapienza University of Rome, Policlinico Umberto Primo, Viale Regina Elena 324, 00161 Rome, ItalyMerkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.http://dx.doi.org/10.1155/2013/131695 |
spellingShingle | Daniele Rossini Salvatore Caponnetto Vittoria Lapadula Lucilla De Filippis Gabriella Del Bene Alessandra Emiliani Flavia Longo Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site Case Reports in Oncological Medicine |
title | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_full | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_fullStr | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_full_unstemmed | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_short | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_sort | merkel cell carcinoma of the retroperitoneum with no identifiable primary site |
url | http://dx.doi.org/10.1155/2013/131695 |
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