Dystrophic phenotype improvement in the diaphragm muscle of mdx mice by diacerhein.
Chronic inflammation and oxidative stress are striking features of Duchenne muscular dystrophy disease. Diacerhein is an anthraquinone, which exhibits anti-inflammatory and antioxidant properties. Based on their actions, the present study evaluated the effects of diacerhein against myonecrosis, oxid...
Saved in:
| Main Authors: | Rafael Dias Mâncio, Túlio de Almeida Hermes, Aline Barbosa Macedo, Daniela Sayuri Mizobuti, Ian Feller Rupcic, Elaine Minatel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182449&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Use of Creatine Monohydrate in MDX Mice: Morphometric and Stereological Analysis of the Diaphragm
by: Victor Augusto Ramos FERNANDES, et al.
Published: (2023-09-01) -
Spatial and age-related changes in the microstructure of dystrophic and healthy diaphragms.
by: Catherine C Henry, et al.
Published: (2017-01-01) -
Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
by: Jonathon M Tinsley, et al.
Published: (2011-05-01) -
APE1/Ref‐1 inhibition via APX3330 lowers monocyte/macrophage infiltration without ameliorating the structure and function of dystrophic mdx hindlimb muscles
by: Hannah Lalunio, et al.
Published: (2025-08-01) -
Skeletal muscle-specific ablation of gamma(cyto)-actin does not exacerbate the mdx phenotype.
by: Kurt W Prins, et al.
Published: (2008-06-01)