A multi-omics study of magnesium sulfate to improve prognosis in sepsis-related encephalopathy: integrating clinical data-driven network pharmacology

A multi-omics study of magnesium sulfate to improve prognosis in sepsis-related encephalopathy: integrating clinical data-driven network pharmacology

BackgroundSepsis-associated encephalopathy (SAE) constitutes a significant neurological manifestation of sepsis, characterized by high mortality rates and posing a critical threat to patient outcomes. Magnesium sulfate has multiple effects in the nervous system, including neuroprotection, sedation,...

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Bibliographic Details
Main Authors: Yingming Kong, Yanghao Tai, Bin Chen, Meng Zhang, Haoyu Ji, Rongke Feng, Liang Shi, Hao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
magnesium sulfate
SAE
mortality
MIMIC-IV database
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1607586/full
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