Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report

ABSTRACT Background The most frequent type of non‐Hodgkin lymphoma (NHL) is diffuse large B‐cell lymphoma (DLBCL). Although lymph nodes are the most commonly affected organs compromising 70% of DLBCLs, only 5% of extranodal lymphomas represent skeletal muscle involvement. Specifically, abdominal wal...

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Main Authors: Somar Mansour, Seif‐Aldin Abdul Rahman, Majd Mansour, Ali Afif, Raghad Hasan, Nader Abdullah, Zuheir Alshehabi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Cancer Reports
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Online Access:https://doi.org/10.1002/cnr2.70114
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author Somar Mansour
Seif‐Aldin Abdul Rahman
Majd Mansour
Ali Afif
Raghad Hasan
Nader Abdullah
Zuheir Alshehabi
author_facet Somar Mansour
Seif‐Aldin Abdul Rahman
Majd Mansour
Ali Afif
Raghad Hasan
Nader Abdullah
Zuheir Alshehabi
author_sort Somar Mansour
collection DOAJ
description ABSTRACT Background The most frequent type of non‐Hodgkin lymphoma (NHL) is diffuse large B‐cell lymphoma (DLBCL). Although lymph nodes are the most commonly affected organs compromising 70% of DLBCLs, only 5% of extranodal lymphomas represent skeletal muscle involvement. Specifically, abdominal wall muscle involvement is rare and there are only a few reported cases of DLBCL with this type of muscle involvement. Painful abdominal mass was the main presenting symptom in these reported cases. Case We are reporting a relapsed DLBCL with abdominal wall muscle involvement in a 65‐year‐old male, presenting with a discomfort and heaviness sensation in the right iliac region with no associated pain. Conclusion A rare case of DLBCL with recurrence in the abdominal wall muscles as painless masses was reported in this case report. To our knowledge, it is considered the fourth reported in the medical literature. It shows the importance of the diagnostic process that combines imaging with histological examination and immune stains for accurate diagnosis.
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institution Kabale University
issn 2573-8348
language English
publishDate 2025-01-01
publisher Wiley
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series Cancer Reports
spelling doaj-art-4e94d2c85a79484e9ba23d3901d167242025-01-30T15:46:35ZengWileyCancer Reports2573-83482025-01-0181n/an/a10.1002/cnr2.70114Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case ReportSomar Mansour0Seif‐Aldin Abdul Rahman1Majd Mansour2Ali Afif3Raghad Hasan4Nader Abdullah5Zuheir Alshehabi6Cancer Research Center Tishreen University Hospital Latakia SyriaCancer Research Center Tishreen University Hospital Latakia SyriaFaculty of Medicine Tishreen University Latakia SyriaFaculty of Medicine Tishreen University Latakia SyriaFaculty of Medicine Tishreen University Latakia SyriaDepartment of Oncology Tishreen University Hospital Latakia SyriaCancer Research Center Tishreen University Hospital Latakia SyriaABSTRACT Background The most frequent type of non‐Hodgkin lymphoma (NHL) is diffuse large B‐cell lymphoma (DLBCL). Although lymph nodes are the most commonly affected organs compromising 70% of DLBCLs, only 5% of extranodal lymphomas represent skeletal muscle involvement. Specifically, abdominal wall muscle involvement is rare and there are only a few reported cases of DLBCL with this type of muscle involvement. Painful abdominal mass was the main presenting symptom in these reported cases. Case We are reporting a relapsed DLBCL with abdominal wall muscle involvement in a 65‐year‐old male, presenting with a discomfort and heaviness sensation in the right iliac region with no associated pain. Conclusion A rare case of DLBCL with recurrence in the abdominal wall muscles as painless masses was reported in this case report. To our knowledge, it is considered the fourth reported in the medical literature. It shows the importance of the diagnostic process that combines imaging with histological examination and immune stains for accurate diagnosis.https://doi.org/10.1002/cnr2.70114abdominalDLBCLlymphomamusclepainless
spellingShingle Somar Mansour
Seif‐Aldin Abdul Rahman
Majd Mansour
Ali Afif
Raghad Hasan
Nader Abdullah
Zuheir Alshehabi
Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report
Cancer Reports
abdominal
DLBCL
lymphoma
muscle
painless
title Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report
title_full Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report
title_fullStr Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report
title_full_unstemmed Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report
title_short Relapse of Diffuse Large B‐Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report
title_sort relapse of diffuse large b cell lymphoma as painless masses in the abdominal wall muscles a rare case report
topic abdominal
DLBCL
lymphoma
muscle
painless
url https://doi.org/10.1002/cnr2.70114
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