Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients

Variables which are of influence in establishing clear predictions of neuropsychological alterations from neuroradiological data (and vice versa) are documented and discussed. It is concluded that personality factors and the kind and locus of brain lesions are the most crucial determinants. The locu...

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Main Authors: Hans J. Markowitsch, Pasquale Calabrese
Format: Article
Language:English
Published: Wiley 1996-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.3233/BEN-1996-9201
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author Hans J. Markowitsch
Pasquale Calabrese
author_facet Hans J. Markowitsch
Pasquale Calabrese
author_sort Hans J. Markowitsch
collection DOAJ
description Variables which are of influence in establishing clear predictions of neuropsychological alterations from neuroradiological data (and vice versa) are documented and discussed. It is concluded that personality factors and the kind and locus of brain lesions are the most crucial determinants. The locus of the brain damage may have cumulative effects either when it is situated in a strategic place (usually within the white matter, affecting interneuronal communication) or when various types of lesions appear superimposed (combination of focal and diffuse lesions). Consequently, the consideration of the patient's personality background and of as many neuropsychological facts as possible may considerably increase the validity of outcome predictions. When static or dynamic neuroimaging fails to show abnormalities in spite of obvious psychological alterations, an intensive neuropsychological documentation may even replace neuroradiology.
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spelling doaj-art-4e80ac9048814f31bf88f2833403a4822025-02-03T06:46:56ZengWileyBehavioural Neurology0953-41801875-85841996-01-0192455510.3233/BEN-1996-9201Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged PatientsHans J. Markowitsch0Pasquale Calabrese1Physiological Psychology, University of Bielefeld, Bielefeld, GermanyPhysiological Psychology, University of Bielefeld, Bielefeld, GermanyVariables which are of influence in establishing clear predictions of neuropsychological alterations from neuroradiological data (and vice versa) are documented and discussed. It is concluded that personality factors and the kind and locus of brain lesions are the most crucial determinants. The locus of the brain damage may have cumulative effects either when it is situated in a strategic place (usually within the white matter, affecting interneuronal communication) or when various types of lesions appear superimposed (combination of focal and diffuse lesions). Consequently, the consideration of the patient's personality background and of as many neuropsychological facts as possible may considerably increase the validity of outcome predictions. When static or dynamic neuroimaging fails to show abnormalities in spite of obvious psychological alterations, an intensive neuropsychological documentation may even replace neuroradiology.http://dx.doi.org/10.3233/BEN-1996-9201
spellingShingle Hans J. Markowitsch
Pasquale Calabrese
Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients
Behavioural Neurology
title Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients
title_full Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients
title_fullStr Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients
title_full_unstemmed Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients
title_short Commonalities and Discrepancies in the Relationships between Behavioural Outcome and the Results of Neuroimaging in Brain-Damaged Patients
title_sort commonalities and discrepancies in the relationships between behavioural outcome and the results of neuroimaging in brain damaged patients
url http://dx.doi.org/10.3233/BEN-1996-9201
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