Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature

Abstract Background Carcinosarcoma is a rare tumor that includes both carcinoma and sarcoma components. It develops commonly in the female reproductive tract, most often in the uterus. However, as there are a small number of similar cases in the English literature, we would like to present a rare ca...

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Main Authors: Rumi Itoyama, Yo-ichi Yamashita, Yosuke Nakao, Toshihiko Yusa, Naoki Umezaki, Takanobu Yamao, Shigeki Nakagawa, Hirohisa Okabe, Katsunori Imai, Hiromitsu Hayashi, Daisuke Hashimoto, Akira Chikamoto, Hideo Baba
Format: Article
Language:English
Published: Japan Surgical Society 2019-01-01
Series:Surgical Case Reports
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Online Access:http://link.springer.com/article/10.1186/s40792-019-0575-z
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author Rumi Itoyama
Yo-ichi Yamashita
Yosuke Nakao
Toshihiko Yusa
Naoki Umezaki
Takanobu Yamao
Shigeki Nakagawa
Hirohisa Okabe
Katsunori Imai
Hiromitsu Hayashi
Daisuke Hashimoto
Akira Chikamoto
Hideo Baba
author_facet Rumi Itoyama
Yo-ichi Yamashita
Yosuke Nakao
Toshihiko Yusa
Naoki Umezaki
Takanobu Yamao
Shigeki Nakagawa
Hirohisa Okabe
Katsunori Imai
Hiromitsu Hayashi
Daisuke Hashimoto
Akira Chikamoto
Hideo Baba
author_sort Rumi Itoyama
collection DOAJ
description Abstract Background Carcinosarcoma is a rare tumor that includes both carcinoma and sarcoma components. It develops commonly in the female reproductive tract, most often in the uterus. However, as there are a small number of similar cases in the English literature, we would like to present a rare case of a carcinosarcoma in Vater’s papilla. Case presentation A 76-year-old female patient was preoperatively diagnosed with a papillary adenocarcinoma in Vater’s papilla by endoscopic biopsy. The patient underwent subtotal stomach-preserving pancreaticoduodenectomy, and postoperative pathological examination diagnosed the carcinosarcoma. The patient received adjuvant chemotherapy with gemcitabine, but multiple liver metastases were found 3 months after the operation. Though chemotherapy with gemcitabine and cisplatin was introduced, she died owing to tumor progression 7 months after the operation. Conclusion Because carcinosarcoma of Vater’s papilla is a rare disease, a suitable treatment strategy has been unclear. We also present a review of the English literature regarding carcinosarcoma of Vater’s papilla.
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publishDate 2019-01-01
publisher Japan Surgical Society
record_format Article
series Surgical Case Reports
spelling doaj-art-4e7a879c4b9d4fe8a3a20f4c18d9d5e82025-08-20T03:14:41ZengJapan Surgical SocietySurgical Case Reports2198-77932019-01-01511510.1186/s40792-019-0575-zCarcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literatureRumi Itoyama0Yo-ichi Yamashita1Yosuke Nakao2Toshihiko Yusa3Naoki Umezaki4Takanobu Yamao5Shigeki Nakagawa6Hirohisa Okabe7Katsunori Imai8Hiromitsu Hayashi9Daisuke Hashimoto10Akira Chikamoto11Hideo Baba12Department of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesDepartment of Gastroenterological Surgery, Kumamoto University Graduate School of Medical SciencesAbstract Background Carcinosarcoma is a rare tumor that includes both carcinoma and sarcoma components. It develops commonly in the female reproductive tract, most often in the uterus. However, as there are a small number of similar cases in the English literature, we would like to present a rare case of a carcinosarcoma in Vater’s papilla. Case presentation A 76-year-old female patient was preoperatively diagnosed with a papillary adenocarcinoma in Vater’s papilla by endoscopic biopsy. The patient underwent subtotal stomach-preserving pancreaticoduodenectomy, and postoperative pathological examination diagnosed the carcinosarcoma. The patient received adjuvant chemotherapy with gemcitabine, but multiple liver metastases were found 3 months after the operation. Though chemotherapy with gemcitabine and cisplatin was introduced, she died owing to tumor progression 7 months after the operation. Conclusion Because carcinosarcoma of Vater’s papilla is a rare disease, a suitable treatment strategy has been unclear. We also present a review of the English literature regarding carcinosarcoma of Vater’s papilla.http://link.springer.com/article/10.1186/s40792-019-0575-zCarcinosarcomaVater’s papillaStomach-preserving pancreaticoduodenectomyChemotherapy
spellingShingle Rumi Itoyama
Yo-ichi Yamashita
Yosuke Nakao
Toshihiko Yusa
Naoki Umezaki
Takanobu Yamao
Shigeki Nakagawa
Hirohisa Okabe
Katsunori Imai
Hiromitsu Hayashi
Daisuke Hashimoto
Akira Chikamoto
Hideo Baba
Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature
Surgical Case Reports
Carcinosarcoma
Vater’s papilla
Stomach-preserving pancreaticoduodenectomy
Chemotherapy
title Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature
title_full Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature
title_fullStr Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature
title_full_unstemmed Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature
title_short Carcinosarcoma of Vater’s papilla: case report of a rare neoplasm and review of the literature
title_sort carcinosarcoma of vater s papilla case report of a rare neoplasm and review of the literature
topic Carcinosarcoma
Vater’s papilla
Stomach-preserving pancreaticoduodenectomy
Chemotherapy
url http://link.springer.com/article/10.1186/s40792-019-0575-z
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