VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease
Dopamine is transported into synaptic vesicles by the vesicular monoamine transporter (VMAT2; SLC18A2). Disruption of dopamine storage has been hypothesized to damage the dopamine neurons that are lost in Parkinson's disease. By disrupting vesicular storage of dopamine and other monoamines, we...
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Main Authors: | Tonya N. Taylor, W. Michael Caudle, Gary W. Miller |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | Parkinson's Disease |
Online Access: | http://dx.doi.org/10.4061/2011/124165 |
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