Acute Demyelination in a Person with Amphetamine Abuse

We report the case of a 31-year-old woman, admitted to the hospital for chest pain, dying a few days later from septic multiorgan failure, and showing at autopsy foci of acute demyelination in the occipital lobe. Gas chromatography/mass spectrometry analysis revealed the presence of amphetamine in t...

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Main Authors: Serge Weis, Hans Sachs, Andreas Büttner
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2011/514613
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author Serge Weis
Hans Sachs
Andreas Büttner
author_facet Serge Weis
Hans Sachs
Andreas Büttner
author_sort Serge Weis
collection DOAJ
description We report the case of a 31-year-old woman, admitted to the hospital for chest pain, dying a few days later from septic multiorgan failure, and showing at autopsy foci of acute demyelination in the occipital lobe. Gas chromatography/mass spectrometry analysis revealed the presence of amphetamine in the demyelinated area, which might be considered as the pathogenic agent, since other causes for demyelination could be excluded. This case represents the first report showing a demyelinating process due to a street drug.
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series Case Reports in Pathology
spelling doaj-art-4e78951c942e4e218827111b293c560e2025-08-20T02:38:48ZengWileyCase Reports in Pathology2090-67812090-679X2011-01-01201110.1155/2011/514613514613Acute Demyelination in a Person with Amphetamine AbuseSerge Weis0Hans Sachs1Andreas Büttner2Laboratory of Neuropathology, Department of Pathology and Neuropathology, State Neuropsychiatric Hospital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020 Linz, AustriaInstitute of Legal Medicine, University of Rostock, 18055 Rostock, GermanyInstitute of Legal Medicine, University of Rostock, 18055 Rostock, GermanyWe report the case of a 31-year-old woman, admitted to the hospital for chest pain, dying a few days later from septic multiorgan failure, and showing at autopsy foci of acute demyelination in the occipital lobe. Gas chromatography/mass spectrometry analysis revealed the presence of amphetamine in the demyelinated area, which might be considered as the pathogenic agent, since other causes for demyelination could be excluded. This case represents the first report showing a demyelinating process due to a street drug.http://dx.doi.org/10.1155/2011/514613
spellingShingle Serge Weis
Hans Sachs
Andreas Büttner
Acute Demyelination in a Person with Amphetamine Abuse
Case Reports in Pathology
title Acute Demyelination in a Person with Amphetamine Abuse
title_full Acute Demyelination in a Person with Amphetamine Abuse
title_fullStr Acute Demyelination in a Person with Amphetamine Abuse
title_full_unstemmed Acute Demyelination in a Person with Amphetamine Abuse
title_short Acute Demyelination in a Person with Amphetamine Abuse
title_sort acute demyelination in a person with amphetamine abuse
url http://dx.doi.org/10.1155/2011/514613
work_keys_str_mv AT sergeweis acutedemyelinationinapersonwithamphetamineabuse
AT hanssachs acutedemyelinationinapersonwithamphetamineabuse
AT andreasbuttner acutedemyelinationinapersonwithamphetamineabuse