Exercise-induced CLCF1 attenuates age-related muscle and bone decline in mice

Exercise-induced CLCF1 attenuates age-related muscle and bone decline in mice

Abstract Skeletal muscle undergoes many alterations with aging. However, the impact of aging on muscle’s ability to secrete myokines and its subsequent effects on the body remain largely unexplored. Here, we identify myokines that have the potential to ameliorate age-related muscle and bone decline....

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Main Authors: Jae Sook Kang, Jung Ha Kim, Min Ju Kim, Byungkuk Min, Seung-Min Lee, Ga-Yeon Go, Ji-Won Kim, Seongwan Kim, Ju Yeon Kwak, Sung-Wook Chun, Wook Song, Hyo Youl Moon, Sun Gun Chung, Dong-Ho Park, Ji Hoon Park, Chuna Kim, Kwang-Pyo Lee, Eun-Soo Kwon, Nacksung Kim, Ki-Sun Kwon, Yong Ryoul Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59959-w
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