Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.

Genome-wide association (GWA) studies have identified a number of loci underlying variation in human serum uric acid (SUA) levels with the SLC2A9 gene having the largest effect identified so far. Gene-gene interactions (epistasis) are largely unexplored in these GWA studies. We performed a full pair...

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Main Authors: Wenhua Wei, Gibran Hemani, Andrew A Hicks, Veronique Vitart, Claudia Cabrera-Cardenas, Pau Navarro, Jennifer Huffman, Caroline Hayward, Sara A Knott, Igor Rudan, Peter P Pramstaller, Sarah H Wild, James F Wilson, Harry Campbell, Malcolm G Dunlop, Nicholas Hastie, Alan F Wright, Chris S Haley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023836&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023836&type=printable

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