Comparison of methods to handle missing values in a continuous index test in a diagnostic accuracy study – a simulation study

Abstract Background Most diagnostic accuracy studies have applied a complete case analysis (CCA) or single imputation approach to address missing values in the index test, which may lead to biased results. Therefore, this simulation study aims to compare the performance of different methods in estim...

Full description

Saved in:
Bibliographic Details
Main Authors: Katharina Stahlmann, Bastiaan Kellerhuis, Johannes B. Reitsma, Nandini Dendukuri, Antonia Zapf
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-025-02594-2
Tags: Add Tag
No Tags, Be the first to tag this record!