Comparison of methods to handle missing values in a continuous index test in a diagnostic accuracy study – a simulation study
Abstract Background Most diagnostic accuracy studies have applied a complete case analysis (CCA) or single imputation approach to address missing values in the index test, which may lead to biased results. Therefore, this simulation study aims to compare the performance of different methods in estim...
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| Main Authors: | Katharina Stahlmann, Bastiaan Kellerhuis, Johannes B. Reitsma, Nandini Dendukuri, Antonia Zapf |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-025-02594-2 |
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