Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis

Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis

The present study investigates whether transplantation of NSCs treated with T3 alone (T3/NSCs), or in conjunction with GDNF gene (GDNF-T3/NSCs), provides a better therapeutic effect than NSCs for chronic EAE. EAE rats were, respectively, injected with NSCs, T3/NSCs, GDNF-T3/NSCs, and saline at 10 da...

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Bibliographic Details
Main Authors:	Xiaoqing Gao, Guangqiang Hu, Li Deng, Guangbi Fan, Chaoxian Yang, Jie Du
Format:	Article
Language:	English
Published:	Wiley 2016-01-01
Series:	Neural Plasticity
Online Access:	http://dx.doi.org/10.1155/2016/3081939
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